Modelling to inform prophylaxis regimens to prevent human rabies (Publications)
BACKGROUND: The Strategic Advisory Group of Experts (SAGE) Working Group on rabies vaccines and immunoglobulins was established in 2016 to develop practical and feasible recommendations for prevention
The origins of malaria artemisinin resistance defined by a genetic and transcriptomic background (Publications)
The predisposition of parasites acquiring artemisinin resistance still remains unclear beyond the mutations in Pfk13 gene and modulation of the unfolded protein response pathway. To explore the chain
The phylogeography and incidence of multi-drug resistant typhoid fever in sub-Saharan Africa (Publications)
There is paucity of data regarding the geographical distribution, incidence, and phylogenetics of multi-drug resistant (MDR) Salmonella Typhi in sub-Saharan Africa. Here we present a phylogenetic reco
Integrated <em>Aedes</em> management for the control of <em>Aedes</em>-borne diseases (Publications)
BACKGROUND: Diseases caused by Aedes-borne viruses, such as dengue, Zika, chikungunya, and yellow fever, are emerging and reemerging globally. The causes are multifactorial and include global trade, i
Drug discovery for kinetoplastid diseases: future directions (Publications)
Kinetoplastid parasites have caused human disease for millennia. Significant achievements have been made toward developing new treatments for leishmaniasis (particularly on the Indian subcontinent) an
Use of recombinant ApxIV in serodiagnosis of <em>Actinobacillus pleuropneumoniae</em> infections, development and prevalidation of the ApxIV ELISA (Publications)
Actinobacillus pleuropneumoniae is the etiological agent of porcine pleuropneumonia, which causes worldwide severe losses in pig farming. The virulence of the 15 serotypes of A. pleuropneumoniae is ma
Leptospira seroprevalence and risk factors in health centre patients in Hoima District, Western Uganda (Publications)
BACKGROUND: The burden of human leptospirosis in Uganda is unknown. We estimated the seroprevalence of Leptospira antibodies, probable acute/recent leptospirosis, and risk factors for seropositivity i
Effects of hydroxyethyl starch 130/0.4 on serum creatinine concentration and development of acute kidney injury in nonazotemic cats (Publications)
BACKGROUND: Hydroxyethyl-starch (HES) solutions might have renal adverse effects in humans and dogs. OBJECTIVE: To determine if administration of 6% HES-130/0.4 is associated with an increase in serum
Never seen before? Opisthorchiasis and Clonorchiasis (Publications)
Parasitic diseases are relatively rarely diagnosed and treated in Europe. Therefore, European clinicians are not familiar with their clinical and imaging features. In an era of increased human migrati