Particulate matter and subclinical atherosclerosis: associations between different particle sizes and sources with carotid intima-media thickness in... (Publications)
BACKGROUND: Subclinical atherosclerosis has been associated with long-term exposure to particulate matter (PM), but the relevance of particle size and sources of exposure remains unclear. OBJECTIVES:
Air pollution, climate and pollen comparisons in urban, rural and alpine regions in Switzerland (Publications)
The aim of this paper is to show spatial differences and correlations in long- term air pollution measurements in the eight SAPALDIA sites (Swiss Study on Air Pollution and Lung Diseases in Adults, SA
Genome-wide association and functional follow-up reveals new loci for kidney function (Publications)
Chronic kidney disease (CKD) is an important public health problem with a genetic component. We performed genome-wide association studies in up to 130,600 European ancestry participants overall, and s
1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function (Publications)
HapMap imputed genome-wide association studies (GWAS) have revealed > 50 loci at which common variants with minor allele frequency > 5% are associated with kidney function. GWAS using more complete re
Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies (Publications)
BACKGROUND: Epigenetic variations in peripheral blood have potential as biomarkers for disease. This systematic review assesses the association of lung function and chronic obstructive pulmonary disea
Infectious diseases are associated with carotid intima media thickness in adolescence (Publications)
OBJECTIVE: Inflammatory risk factors in childhood, e.g. obesity, impact on carotid artery intima media thickness (CIMT), an early indicator of atherosclerosis. Little is known on potential infectious
The adverse impact of obesity on heart rate variability is modified by a <em>NFE2L2 </em>gene variant: the SAPALDIA Cohort (Publications)
BACKGROUND: Overweight has been associated with an increase in inflammatory markers and with an imbalance in the autonomic nervous system, such as a decrease in heart rate variability (HRV). In this s
Heterogeneity of obesity-asthma association disentangled by latent class analysis, the SAPALDIA cohort (Publications)
Although evidence for the heterogeneity of asthma accumulated, consensus for definitions of asthma phenotypes is still lacking. Obesity may have heterogeneous effects on various asthma phenotypes. We
Carotid stiffness and physical activity in elderly: a short report of the SAPALDIA 3 cohort study (Publications)
INTRODUCTION: Regular physical activity has been shown to reduce cardiovascular disease risk in the general population. While smaller studies in specified groups (highly trained versus untrained indiv