Sex-specific associations of cardiovascular risk factors with carotid stiffness - results from the SAPALDIA cohort study (Publications)
OBJECTIVE: Manifestation of cardiovascular disease (CVD) occurs with clear sex differences. Carotid stiffness (CS) parameters are increasingly used for CVD risk assessment but the sex-specific associa
Reproducibility of oscillometrically measured arterial stiffness indices: results of the SAPALDIA 3 cohort study (Publications)
Background. There is an increasing interest in oscillometric arterial stiffness measurement for cardiovascular risk stratification. We assessed reproducibility of the cuff-based arterial stiffness mea
Association of ambient air pollution with the prevalence and incidence of COPD (Publications)
The role of air pollution in chronic obstructive pulmonary disease (COPD) remains uncertain. The aim was to assess the impact of chronic exposure to air pollution on COPD in four cohorts using the sta
Physical activity is associated with lower arterial stiffness in older adults: results of the SAPALDIA 3 cohort study (Publications)
Associations of physical activity (PA) intensity with arterial stiffness in older adults at the population level are insufficiently studied. We examined cross-sectional associations of self-reported P
Is there a differential impact of parity on blood pressure by age? (Publications)
OBJECTIVE: In pregnancy, women experience metabolic and hemodynamic changes of potential long-term impact. Conflicting evidence exists on the impact on blood pressure (BP). We investigated the associa
Modelling the health and economic impacts of the elimination of river blindness (onchocerciasis) in Africa (Publications)
BACKGROUND: Onchocerciasis (river blindness) is endemic mostly in remote and rural areas in sub-Saharan Africa. The treatment goal for onchocerciasis has shifted from control to elimination in Africa.
Tuberculosis treatment outcomes among HIV/TB-coinfected children in the International Epidemiology Databases to Evaluate AIDS (IeDEA) network (Publications)
INTRODUCTION: Management of tuberculosis (TB) is challenging in HIV/TB-coinfected children. The World Health Organization recommends nucleic acid amplification tests for TB diagnosis, a 4-drug regimen
Hit-to-lead optimization of a novel class of potent, broad-spectrum trypanosomacides (Publications)
The parasitic trypanosomes Trypanosoma brucei and T. cruzi are responsible for significant human suffering in the form of human African trypanosomiasis (HAT) and Chagas disease. Drugs currently availa