Efficacy study of novel diamidine compounds in a <em>Trypanosoma evansi</em> goat model (Publications)
Three diamidines (DB 75, DB 867 and DB 1192) were selected and their ability to cure T. evansi experimentally infected goats was investigated. A toxicity assessment and pharmacokinetic analysis of the
A randomized placebo-controlled phase a malaria vaccine trial of two virosome-formulated synthetic peptides in healthy adult volunteers (Publications)
BACKGROUND AND OBJECTIVES: Influenza virosomes represent an innovative human-compatible antigen delivery system that has already proven its suitability for subunit vaccine design. The aim of the study
Crying babies, tired mothers - challenges of the postnatal hospital stay: an interpretive phenomenological study (Publications)
ABSTRACT: BACKGROUND: According to an old Swiss proverb, "a new mother lazing in childbed is a blessing to her family". Today mothers rarely enjoy restful days after birth, but enter directly into the
Chemometric analysis of biofluids from mice experimentally infected with <em>Schistosoma mansoni</em> (Publications)
ABSTRACT: BACKGROUND: The urinary metabolic fingerprint of a patent Schistosoma mansoni infection in the mouse has been characterized using spectroscopic methods. However, the temporal dynamics of met
Comparative analysis of <em>Mycobacterium tuberculosis</em> <em>pe </em>and <em>ppe</em> genes reveals high sequence variation and an apparent absence... (Publications)
Mycobacterium tuberculosis complex (MTBC) genomes contain 2 large gene families termed pe and ppe. The function of pe/ppe proteins remains enigmatic but studies suggest that they are secreted or cell
Genome-wide identification of molecular mimicry candidates in parasites (Publications)
Among the many strategies employed by parasites for immune evasion and host manipulation, one of the most fascinating is molecular mimicry. With genome sequences available for host and parasite, mimic
Chronic age-related diseases share risk factors: do they share pathophysiological mechanisms and why does that matter? (Publications)
The World Health Organization (WHO) assigns high priority to the prevention of non-communicable age-related diseases such as heart disease, cancer, diabetes, stroke and chronic lower respiratory disea