Spatio-temporal analysis to identify determinants of <em>Oncomelania hupensis</em> infection with <em>Schistosoma japonicum</em> in Jiangsu province,... (Publications)
BACKGROUND: With the successful implementation of integrated measures for schistosomiasis control, Jiangsu province has reached low-endemicity status. However, infected Oncomelania hupensis snails cou
Rapid urban malaria appraisal (RUMA) IV: epidemiology of urban malaria in Cotonou (Benin) (Publications)
BACKGROUND: An estimated 40 % of the population in Benin lives in urban areas. The purpose of the study was to estimate malaria endemicity and the fraction of malaria-attributable fevers in health fac
Out-of-pocket expenditures for primary health care in Tajikistan: a time-trend analysis (Publications)
BACKGROUND: Aligned with the international call for universal coverage of affordable and quality health care, the government of Tajikistan is undertaking reforms of its health system aiming amongst ot
Community-based surveillance of malaria vector larval habitats: a baseline study in urban Dar es Salaam, Tanzania (Publications)
ABSTRACT: BACKGROUND: As the population of Africa rapidly urbanizes it may be possible to protect large populations from malaria by controlling aquatic stages of mosquitoes. Here we present a baseline
A new double-antibody sandwich ELISA targeting <em>Plasmodium falciparum</em> aldolase to evaluate anti-malarial drug sensitivity (Publications)
BACKGROUND: The standard in vitro test to assess anti-malarial activity of chemical compounds is the [3H]hypoxanthine incorporation assay. It is a radioactivity-based method to measure DNA replication
A research agenda for malaria eradication: vector control (Publications)
Different challenges are presented by the variety of malaria transmission environments present in the world today. In each setting, improved control for reduction of morbidity is a necessary first ste
Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism (Publications)
BACKGROUND AND METHODOLOGY: Recently, we reported on a new class of naphthoquinone derivatives showing a promising anti-trypanosomatid profile in cell-based experiments. The lead of this series (B6, 2