Activity of oxantel pamoate monotherapy and combination chemotherapy against <em>Trichuris muris</em> and hookworms: revival of an old drug (Publications)
BACKGROUND: It is widely recognized that only a handful of drugs are available against soil-transmitted helminthiasis, all of which are characterized by a low efficacy against Trichuris trichiura, whe
Air pollution and atherosclerosis: new evidence to support air quality policies (Publications)
Nino Künzli discusses a large new cohort study that provides some of the first human evidence for the impact of air pollution on the development of atherosclerosis.
Genetic characterization of<em> Legionella pneumophila</em> isolated from a common watershed in Comunidad Valenciana, Spain (Publications)
Legionella pneumophila infects humans to produce legionellosis and Pontiac fever only from environmental sources. In order to establish control measures and study the sources of outbreaks it is essent
<em>In vitro</em> and <em>in vivo</em> efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections (Publications)
BACKGROUND: Few effective drugs are available for soil-transmitted helminthiases and drug resistance is of concern. In the present work, we tested the efficacy of the veterinary drug monepantel, a pot
Comparison of <em>Plasmodium falciparum</em> allelic frequency distribution in different endemic settings by high-resolution genotyping (Publications)
BACKGROUND: The diversity of genotyping markers of Plasmodium falciparum depends on transmission intensity. It has been reported that the diversity of the merozoite surface protein 2 (msp2) is greater
<em>Anopheles plumbeus</em> (Diptera: Culicidae) in Europe: a mere nuisance mosquito or potential malaria vector? (Publications)
ABSTRACT: BACKGROUND: Anopheles plumbeus has been recognized as a minor vector for human malaria in Europe since the beginning of the 20th century. In recent years this tree hole breeding mosquito spe
Rapid and accurate detection of <em>Mycobacterium tuberculosis</em> in sputum samples by Cepheid Xpert MTB/RIF assay - a clinical validation study (Publications)
BACKGROUND: A crucial impediment to global tuberculosis control is the lack of an accurate, rapid diagnostic test for detection of patients with active TB. A new, rapid diagnostic method, (Cepheid) Xp
Specificity of human immunodeficiency virus (LAV/HTLV-III)-reactive antibodies in African sera from southeastern Tanzania (Publications)
The prevalence of antibodies to human immunodeficiency virus (HIV = LAV/HTLV-III) in a rural population from the Ifakara area in southeastern Tanzania was investigated. Sera from 286 individuals colle