The activities of current antimalarial drugs on the life cycle stages of <em>Plasmodium</em>: a comparative study with human and rodent parasites (Publications)
BACKGROUND: Malaria remains a disease of devastating global impact, killing more than 800,000 people every year-the vast majority being children under the age of 5. While effective therapies are avail
Modelling the cost-effectiveness of mass screening and treatment for reducing <em>Plasmodium falciparum</em> malaria burden (Publications)
BACKGROUND: Past experience and modelling suggest that, in most cases, mass treatment strategies are not likely to succeed in interrupting Plasmodium falciparum malaria transmission. However, this doe
The interrelation between premenstrual syndrome and major depression: results from a population-based sample (Publications)
ABSTRACT: BACKGROUND: Research about the relationship between premenstrual syndrome (PMS) and major depression is limited. This study examined the relationship between moderate to severe PMS and major
Frontiers of parasitology research in the People's Republic of China: infection, diagnosis, protection and surveillance (Publications)
ABSTRACT: Control and eventual elimination of human parasitic diseases in the People's Republic of China (P.R. China) requires novel approaches, particularly in the areas of diagnostics, mathematical
On the origin of <em>Mycobacterium ulcerans</em>, the causative agent of Buruli ulcer (Publications)
ABSTRACT: BACKGROUND: Mycobacterium ulcerans is an unusual bacterial pathogen with elusive origins. While closelyrelated to the aquatic dwelling M. marinum, M. ulcerans has evolved the ability to prod
Implementing new health interventions in developing countries: why do we lose a decade or more? (Publications)
BACKGROUND: It is unclear how long it takes for health interventions to transition from research and development (R&D) to being used against diseases prevalent in resource-poor countries. We undertook
Do existing research summaries on health systems match immunisation managers' needs in middle- and low-income countries? Analysis of GAVI health... (Publications)
ABSTRACT: BACKGROUND: The GAVI Alliance was created in 2000 to increase access to vaccines. More recently, GAVI has supported evidence-based health systems strengthening to overcome barriers to vaccin
Paediatric referrals in rural Tanzania: the Kilombero District Study - a case series (Publications)
BACKGROUND: Referral is a critical part of appropriate primary care and of the Integrated Management of Childhood Illness (IMCI) strategy. We set out to study referrals from the aspect both of primary
Predominance of <em>dfrG</em> as determinant of trimethoprim resistance in imported <em>Staphylococcus aureus</em> (Publications)
To investigate the global occurrence of trimethoprim-sulfamethoxazole resistance and the genetic mechanisms of trimethoprim resistance, we analysed Staphylococcus aureus from travel-associated skin an