<em>Plasmodium falciparum</em> heterochromatin protein 1 marks genomic loci linked to phenotypic variation of exported virulence factors (Publications)
Epigenetic processes are the main conductors of phenotypic variation in eukaryotes. The malaria parasite Plasmodium falciparum employs antigenic variation of the major surface antigen PfEMP1, encoded
Virosome-formulated <em>Plasmodium falciparum</em> AMA-1 & CSP derived peptides as malaria vaccine: randomized phase 1b trial in semi-immune... (Publications)
BACKGROUND: This trial was conducted to evaluate the safety and immunogenicity of two virosome formulated malaria peptidomimetics derived from Plasmodium falciparum AMA-1 and CSP in malaria semi-immun
Importance of factors determining the effective lifetime of a mass, long-lasting, insecticidal net distribution: a sensitivity analysis (Publications)
BACKGROUND: Long-lasting insecticidal nets (LLINs) reduce malaria transmission by protecting individuals from infectious bites, and by reducing mosquito survival. In recent years, millions of LLINs ha
Age-patterns of malaria vary with severity, transmission intensity and seasonality in sub-Saharan Africa: a systematic review and pooled analysis (Publications)
BACKGROUND: There is evidence that the age-pattern of Plasmodium falciparum malaria varies with transmission intensity. A better understanding of how this varies with the severity of outcome and acros
Effects of pyrethroid resistance on the cost effectiveness of a mass distribution of long-lasting insecticidal nets: a modelling study (Publications)
BACKGROUND: The effectiveness of insecticide-treated nets in preventing malaria is threatened by developing resistance against pyrethroids. Little is known about how strongly this affects the effectiv
The prevalence of syphilis infection and its associated factors in the general population of Rwanda: a national household-based survey (Publications)
Background. The prevalence of syphilis among HIV-infected people is a public health concern, but there is limited literature to describe the true burden of syphilis in resource-limited settings. We co
How to evaluate health-related quality of life and its association with medication adherence in pulmonary tuberculosis - designing a prospective... (Publications)
INTRODUCTION: Health-related quality of life (HRQOL) has become an important measure to identify and shape effective and patient-relevant healthcare interventions innovations through outcomes. Adheren
Association of vitamin D status with incidence of enterotoxigenic, enteropathogenic and enteroaggregative <em>Escherichia coli</em> diarrhoea in... (Publications)
OBJECTIVE: To evaluate the association between vitamin D status and diarrhoeal episodes by enterotoxigenic (ETEC), enterpathogenic (EPEC) and enteroaggregative (EAEC) E. coli in underweight and normal