Evaluation of the <em>in vitro</em> trypanocidal activity of methylated flavonoid constituents of <em>Vitex simplicifolia</em> leaves (Publications)
BACKGROUND: Trypanosomiasis is a neglected tropical disease with complex clinical manifestations, tedious diagnosis, and difficult treatments. The drugs available for the treatment of this endemic dis
Comparison of detection methods to estimate asexual <em>Plasmodium falciparum</em> parasite prevalence and gametocyte carriage in a community survey... (Publications)
BACKGROUND: The use of molecular techniques to detect malaria parasites has been advocated to improve the accuracy of parasite prevalence estimates, especially in moderate to low endemic settings. Mol
Can smartphones and tablets improve the management of childhood illness in Tanzania? A qualitative study from a primary health care worker's... (Publications)
BACKGROUND: The impact of the Integrated Management of Childhood Illness (IMCI) strategy has been less than anticipated because of poor uptake. Electronic algorithms have the potential to improve qual
Costing the supply chain for delivery of ACT and RDTs in the public sector in Benin and Kenya (Publications)
BackgroundStudies have shown that supply chain costs are a significant proportion of total programme costs. Nevertheless, the costs of delivering specific products are poorly understood and ballpark e
Quality control in the diagnosis of <em>Trichuris trichiura</em> and <em>Ascaris lumbricoides</em> using the Kato-Katz technique: experience from... (Publications)
BackgroundAn accurate diagnosis of soil-transmitted helminthiasis is important for individual patient management, for drug efficacy evaluation and for monitoring control programmes. The Kato-Katz tech
Chemotherapy of second stage human African trypanosomiasis: comparison between the parenteral diamidine DB829 and its oral prodrug DB868 in vervet... (Publications)
Human African trypanosomiasis (HAT, sleeping sickness) ranks among the most neglected tropical diseases based on limited availability of drugs that are safe and efficacious, particularly against the s