Novel inhibitors of <em>Plasmodium falciparum</em> dihydroorotate dehydrogenase with anti-malarial activity in the mouse model (Publications)
Plasmodium falciparum, the causative agent of the most deadly form of human malaria, is unable to salvage pyrimidines and must rely on de novo biosynthesis for survival. Dihydroorotate dehydrogenase (
Fleischkonsum und Serum-Cholesterin-Konzentration (Publications)
In a representative cross-sectional study of the population of Basel, Switzerland (252 men, 281 women, mean age 48 25-74 years), there was a significant association between the consumption of meat and
Treatment of cutaneous leishmaniasis among travellers (Publications)
Leishmaniasis is endemic in 88 countries on five continents. There are 1-1.5 million cases of cutaneous leishmaniasis reported yearly worldwide. There has been a sharp increase in recorded cases over
No further increase in asthma, hay fever and atopic sensitisation in adolescents living in Switzerland (Publications)
Prevalence rates of childhood asthma and allergy have been on the increase for several decades. The present study investigated whether this trend continued during the 1990s in adolescents living in Sw