Exploration of novel<em> in vitro</em> assays to study drugs against <em>Trichuris </em>spp. (Publications)
Though trichuriasis is a significant public health problem, few effective drugs are available underscoring the need for new drug therapies. For the evaluation of trichuricidal activity of test compoun
Acute phase proteins and white blood cell levels for prediction of infectious complications in status epilepticus (Publications)
ABSTRACT: INTRODUCTION: Infections in status epilepticus (SE) patients result in severe morbidity making early diagnosis crucial. As SE may lead to inflammatory reaction, the value of acute phase prot
Socio-cultural determinants of anticipated acceptance of an oral cholera vaccine in western Kenya (Publications)
SUMMARYDeterminants of anticipated acceptance of an oral cholera vaccine (OCV) were studied in urban and rural communities of Western Kenya. An explanatory model interview administered to 379 communit
Compounds structurally related to ellagic acid show improved antiplasmodial activity (Publications)
The cancer chemopreventive agent ellagic acid (EA) is a known inhibitor of glutathione S-transferases (GSTs) and possesses antiplasmodial activities in the upper-nanomolar range. In the recent drug de
Single nucleotide polymorphisms in <em>Mycobacterium tuberculosis</em> and the need for a curated database (Publications)
Recent advances in DNA sequencing have led to the discovery of thousands of single nucleotide polymorphisms (SNPs) in clinical isolates of Mycobacterium tuberculosis complex (MTBC). This genetic varia
Interaction of monobenzamidine-linked trypanocides with the <em>Trypanosoma brucei</em> P2 aminopurine transporter (Publications)
Single benzamidine group-carrying compounds were shown to interact with the Trypanosoma brucei P2 aminopurine transporter. Replacement of the amidine with a guanidine group decreased affinity. Trypano
Spatial analysis of malaria transmission parameters in the rice cultivation area of office du Niger, Mali (Publications)
The effects of rice growth environment on malaria transmission, taking into account spatial correlation, were assessed in the Office du Niger, Mali. Between April 1999 to January 2001, 8 quarterly ent