Immune recovery after starting ART in HIV-infected patients presenting and not presenting with tuberculosis in south Africa (Publications)
We studied the immune response after starting antiretroviral treatment (ART) in 15,646 HIV-infected patients with or without tuberculosis (TB) at presentation in 3 ART programs in South Africa between
Effects of inflammation and <em>Plasmodium falciparum</em> infection on soluble transferrin receptor and plasma ferritin concentration in different... (Publications)
BACKGROUND: Iron deficiency (ID) is a major cause of anemia, along with other nutritional, parasitic, and genetic factors. Accurate biomarkers are needed to estimate the relative contribution of ID to
Optimization of the electrophile of chloronitrobenzamide leads active against <em>Trypanosoma brucei</em> (Publications)
We previously reported the phenylchloronitrobenzamides (PCNBs), a novel class of compounds active against the species of trypanosomes that cause Human African Trypanosomiasis (HAT). Herein, we explore
Asthma and allergies: is the farming environment (still) protective in Poland? The GABRIEL Advanced Studies (Publications)
BACKGROUND: Evidence exists that a farming environment in childhood may provide protection against atopic respiratory disease. In the GABRIEL project based in Poland and Alpine regions of Germany, Aus
Discovery and structure-activity relationships of pyrrolone antimalarials (Publications)
In the pursuit of new antimalarial leads, a phenotypic screening of various commercially sourced compound libraries was undertaken by the World Health Organisation Programme for Research and Training
Prevalence of active convulsive epilepsy in sub-Saharan Africa and associated risk factors: cross-sectional and case-control studies (Publications)
BACKGROUND: The prevalence of epilepsy in sub-Saharan Africa seems to be higher than in other parts of the world, but estimates vary substantially for unknown reasons. We assessed the prevalence and r
Evidence for diversifying selection in a set of <em>Mycobacterium tuberculosis</em> genes in response to antibiotic- and nonantibiotic-related... (Publications)
Tuberculosis (TB) is a global health problem estimated to kill 1.4 million people per year. Recent advances in the genomics of the causative agents of TB, bacteria known as the Mycobacterium tuberculo
Raw fish consumption in liver fluke endemic areas in rural southern Laos (Publications)
Consumption of raw or insufficiently cooked fish is a major public health concern in Southeast Asia, and in Lao People's Democratic Republic (Lao PDR), in particular. We aimed to assess the knowledge,