Cleavage of trypanosome surface glycoproteins by alkaline trypsin-like enzyme(s) in the midgut of <em>Glossina morsitans</em> (Publications)
EP and GPEET procyclin, the major surface glycoproteins of procyclic forms of Trypanosoma brucei, are truncated by proteases in the midgut of the tsetse fly Glossina morsitans morsitans. We show that
Synthesis of a series of N(6)-substituted adenosines with activity against trypanosomatid parasites (Publications)
The involvement of purine salvage in the accumulation of current trypanocidal drugs is important for the treatment of African sleeping sickness. The substrate specificity of essential nucleoside trans
Investigation of the concentration of bacteria and their cell envelope components in indoor air in two elementary schools (Publications)
Bacterial cell envelope components are widely distributed in airborne dust, where they act as inflammatory agents causing respiratory symptoms. Measurements of these agents and other environmental fac
<em>Schistosoma mansoni</em> tetraspanning orphan receptor (SmTOR) - a new vaccine candidate against Schistosomiasis (Publications)
One approach to fight against schistosomiasis is to develop an efficient vaccine. Schistosoma mansoni tetraspanning orphan receptor (SmTOR) might be a vaccine candidate, as it is a tegument membrane p
Exposure assessment of particulate matter for susceptible populations in Seattle (Publications)
In this article we present results from a 2-year comprehensive exposure assessment study that examined the particulate matter (PM) exposures and health effects in 108 individuals with and without chro
Discovery and preliminary structure-activity relationship analysis of 1,14-sperminediphenylacetamides as potent and selective antimalarial lead... (Publications)
Screening of synthesized and isolated marine natural products for in vitro activity against four parasitic protozoa has identified the ascidian metabolite 1,14-sperminedihomovanillamide (orthidine F,