Quantification of self pollution from two diesel school buses using three independent methods (Publications)
We monitored two Seattle school buses to quantify the buses' self pollution using the dual tracers (DT), lead vehicle (LV), and chemical mass balance (CMB) methods. Each bus drove along a residential
Parallel synthesis of a series of non-functional ATP/NAD analogs with activity against trypanosomatid parasites (Publications)
Non-functional analogs of the cofactors ATP and NAD are putative inhibitors of ATP- or NAD-dependant enzymes. Since pathogenic protozoa rely heavily on the salvage of purine nucleosides from the blood
Optimization of purine-nitrile TbcatB inhibitors for use in vivo and evaluation of efficacy in murine models (Publications)
There are currently only four clinical drugs available for treating human African trypanosomiasis (HAT), three of which were developed over 60years ago. Despite years of effort, there has been relativ
Combination of single nucleotide polymorphism and variable-number tandem repeats for genotyping a homogenous population of <em>Mycobacterium... (Publications)
The standard 15- and 24-locus variable-number tandem repeat (VNTR) genotyping methods have demonstrated adequate discriminatory power and a small homoplasy effect for tracing tuberculosis (TB) transmi
Diagnostic genotyping of old and new world <em>Leishmania</em> species by PCR-RFLP (Publications)
We have designed a new genotyping scheme for molecular diagnosis of the different Leishmania species pathogenic to humans. This scheme is based on PCR amplified sequences from the gene for the spliced