2-Phenoxy-1,4-naphthoquinones: from a multitarget antitrypanosomal to a potential antitumor profile (Publications)
A small library of 2-phenoxy-1,4-naphthoquinone and 2-phenoxy-1,4-anthraquinone derivatives was initially developed to optimize the antitrypanosomatid profile of the multitarget hit compound B6 (1). T
Strengthening accountability for improved maternal and newborn health: a mapping of studies in sub-Saharan Africa (Publications)
OBJECTIVE: To describe the types of maternal and newborn health program accountability mechanisms implemented and evaluated in recent years in Sub-Saharan Africa, how these have been implemented, thei
Intestinal parasite infections and associated risk factors in communities exposed to wastewater in urban and peri-urban transition zones in Hanoi,... (Publications)
BACKGROUND: Infections with intestinal parasites (helminths and intestinal protozoa) are endemic in Southeast Asia and inappropriate management and reuse of wastewater might exacerbate the risk of hum
<em>Mycobacterium tuberculosis</em> lineage 4 comprises globally distributed and geographically restricted sublineages (Publications)
Generalist and specialist species differ in the breadth of their ecological niches. Little is known about the niche width of obligate human pathogens. Here we analyzed a global collection of Mycobacte
Can performance-based incentives improve motivation of nurses and midwives in primary facilities in northern Ghana? A quasi-experimental study (Publications)
BACKGROUND: Lack of an adequate and well-performing health workforce has emerged as the biggest barrier to scaling up health services provision in sub-Saharan Africa. As the global community commits t
2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities (Publications)
A library of 2,N(6)-disubstituted adenosine analogs was synthesized and the analogs were tested for their antiprotozoal activities. It was found that 2-methoxy and 2-histamino and N(6)-m-iodobenzyl su
Public health benefits from livestock Rift Valley fever control: a simulation of two epidemics in Kenya (Publications)
In controlling Rift Valley fever, public health sector optimises health benefits by considering cost-effective control options. We modelled cost-effectiveness of livestock RVF control from a public he
Global, regional, national, and selected subnational levels of stillbirths, neonatal, infant, and under-5 mortality, 1980-2015: a systematic analysis... (Publications)
BACKGROUND: Established in 2000, Millennium Development Goal 4 (MDG4) catalysed extraordinary political, financial, and social commitments to reduce under-5 mortality by two-thirds between 1990 and 20
Malaria vectors and their blood-meal sources in an area of high bed net ownership in the western Kenya highlands (Publications)
BACKGROUND: Blood-meal sources of malaria vectors affect their capacity to transmit the disease. Most efficient malaria vectors prefer human hosts. However, with increasing personal protection measure
Asymptomatic only at first sight: malaria infection among schoolchildren in highland Rwanda (Publications)
BACKGROUND: Plasmodium infection and malaria in school children are increasingly recognized as a relevant public health problem, but data on actual prevalence and health consequences are insufficient.