"You can save time if..."-a qualitative study on internal factors slowing down clinical trials in sub-Saharan Africa (Publications)
BACKGROUND: The costs, complexity, legal requirements and number of amendments associated with clinical trials are rising constantly, which negatively affects the efficient conduct of trials. In Sub-S
The shape of the iceberg: quantification of submicroscopic <em>Plasmodium falciparum</em> and<em> Plasmodium vivax </em>parasitaemia and... (Publications)
BACKGROUND: The widespread presence of low-density asymptomatic infections with concurrent gametocytes may be a stumbling block for malaria elimination. This study investigated the asymptomatic reserv
Incidence and risk factors for hypertension among HIV patients in rural Tanzania - a prospective cohort study (Publications)
INTRODUCTION: Scarce data are available on the epidemiology of hypertension among HIV patients in rural sub-Saharan Africa. We explored the prevalence, incidence and risk factors for incident hyperten
Raising more domestic money for health: prospects for low- and middle-income countries (Publications)
Since the 2007/2008 financial crisis, the rhetoric in the development assistance dialogue has shifted away from raising more international funding for health, to requesting countries to move toward se
Exposure of <em>Heligmosomoides polygyrus</em> and <em>Trichuris muris</em> to albendazole, albendazole sulfoxide, mebendazole and oxantel pamoate... (Publications)
Millions of people are treated with anthelmintics to control soil-transmitted helminth infections; yet, drug distribution in the plasma and gastrointestinal tract compartments and the pathway of drug
False-negative malaria rapid diagnostic tests in Rwanda: impact of <em>Plasmodium falciparum</em> isolates lacking <em>hrp2</em> and declining malaria... (Publications)
BACKGROUND: Rapid diagnostic tests (RDTs) for histidine rich protein 2 (HRP2) are often used to determine whether persons with fever should be treated with anti-malarials. However, Plasmodium falcipar
<em>Staphylococcus aureus</em> activates type I IFN signaling in mice and humans through the Xr repeated sequences of protein A (Publications)
The activation of type I IFN signaling is a major component of host defense against viral infection, but it is not typically associated with immune responses to extracellular bacterial pathogens. Usin