Prenatal farm exposure is related to the expression of receptors of the innate immunity and to atopic sensitization in school-age children (Publications)
BACKGROUND: There is increasing evidence that environmental exposures determining childhood illnesses operate early in life. Prenatal exposure to a farming environment through the mother might also pl
Interaction between exposure to dairy farms and polymorphisms in the TLR2 gene determines susceptibility to asthma in European children' (Publications)
Background: The finding that the prevalence of asthma and allergies is less frequent in children raised on animal farms has led to the conjecture that exposure to microbial products modifies immune re
Praziquantel analogs with activity against juvenile<em> Schistosoma mansoni</em> (Publications)
Six amide and four urea derivatives of praziquantel were synthesized and tested for antischistosomal activity against juvenile and adults stages of Schistosoma mansoni in infected mice. Only one of th
<em>In vivo</em> and <em>in vitro</em> sensitivity of <em>Fasciola hepatica</em> to combinations of triclabendazole and artesunate, artemether or OZ78 (Publications)
Triclabendazole resistance is continually documented from livestock and hence new treatment strategies for F. hepatica infections are needed. We investigated the effect of combinations with triclabend
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations (Publications)
Elevated serum urate concentrations can cause gout, a prevalent and painful inflammatory arthritis. By combining data from > 140,000 individuals of European ancestry within the Global Urate Genetics C