hERG,<em> Plasmodium</em> life cycle, and cross resistance profiling of new azabenzimidazole analogues of astemizole (Publications)
Toward addressing the cardiotoxicity liability associated with the antimalarial drug astemizole (AST, hERG IC50 = 0.0042 μM) and its derivatives, we designed and synthesized analogues based on compoun
A new model for ranking schools of public health: the public health academic ranking (Publications)
Objectives: As there is no ranking designed for schools of Public Health, the aim of this project was to create one. Methods: To design the Public Health Academic Ranking (PHAR), we used the InCites B
Phylogenetic analysis of pyruvate-ferredoxin oxidoreductase, a redox enzyme involved in the pharmacological activation of nitro-based prodrugs in... (Publications)
The present frontrunners in the chemotherapy of infections caused by protozoa are nitro-based prodrugs that are selectively activated by PFOR-mediated redox reactions. This study seeks to analyze the
Assessment of diabetes and prediabetes prevalence and predictors by HbA1c in a population from sub-Saharan Africa with a high proportion of anemia: a... (Publications)
INTRODUCTION: Epidemiological data about diabetes mellitus (DM) for sub-Saharan Africa (SSA) are scarce and the utility of glycated hemoglobin (HbA1c) to diagnose DM is uncertain in African population
Digital multiplex ligation assay for highly multiplexed screening of beta-lactamase-encoding genes in bacterial isolates (Publications)
Increasing incidence of antibiotic resistance in clinical and environmental settings calls for increased scalability in their surveillance. Current screening technologies are limited by the number of
A systematic review of chlorine-based surface disinfection efficacy to inform recommendations for low-resource outbreak settings (Publications)
BACKGROUND: Infectious diseases can be transmitted via fomites (contaminated surfaces/objects); disinfection can interrupt this transmission route. However, disinfection guidelines for low-resource ou