Associations between dietary patterns and post-bronchodilation lung function in the SAPALDIA cohort (Publications)
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is not restricted to smokers. Dietary habits may contribute to the disease occurrence. Epidemiological studies point to a protective effect of
Effectiveness of a chlorhexidine dressing on silver-coated external ventricular drain associated colonization/infection - a prospective single-blinded... (Publications)
Background: Observational studies have shown that dressings containing chlorhexidine gluconate (CHX) lower the incidence external ventricular drain (EVD) associated infections (EVDAI). This prospectiv
Epiisopilosine alkaloid has activity against <em>Schistosoma mansoni</em> in mice without acute toxicity (Publications)
Schistosomiasis is a disease caused by parasites of the genus Schistosoma, currently affecting more than 200 million people. Among the various species of this parasite that infect humans, S. mansoni i
Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial... (Publications)
BACKGROUND: Medulloblastoma is associated with rare hereditary cancer predisposition syndromes; however, consensus medulloblastoma predisposition genes have not been defined and screening guidelines f
Repurposing a library of human cathepsin L ligands: identification of macrocyclic lactams as potent rhodesain and <em>trypanosoma brucei... (Publications)
Rhodesain (RD) is a parasitic, human cathepsin L (hCatL) like cysteine protease produced by Trypanosoma brucei ( T. b.) species and a potential drug target for the treatment of human African trypanoso
Drug use in the management of uncomplicated malaria in public health facilities in the Democratic Republic of the Congo (Publications)
BACKGROUND: Malaria the first causes of death from parasitic infection worldwide. Interventions to reduce the burden of malaria have produced a tremendous drop in malaria morbidity and mortality. Howe
Malaria infection in mosquitoes decreases the personal protection offered by permethrin-treated bednets (Publications)
BACKGROUND: Insecticides targeting adult mosquitoes are the main way of controlling malaria. They work not only by killing mosquitoes, but also by repelling and irritating them. Indeed their repellent
Appropriateness of malaria diagnosis and treatment for fever episodes according to patient history and anti-malarial blood measurement: a... (Publications)
BACKGROUND: Monitoring the impact of case management strategies at large scale is essential to evaluate the public health benefit they confer. The use of methodologies relying on objective and standar
A bead-based immunogold-silver staining assay on capillary-driven microfluidics (Publications)
Point-of-care (POC) diagnostics are critically needed for the detection of infectious diseases, particularly in remote settings where accurate and appropriate diagnosis can save lives. However, it is
Interplay of strain and race/ethnicity in the innate immune response to <em>M. tuberculosis</em> (Publications)
BACKGROUND: The roles of host and pathogen factors in determining innate immune responses to M. tuberculosis are not fully understood. In this study, we examined host macrophage immune responses of 3