Exogenous iron increases fasciocidal activity and hepatocellular toxicity of the synthetic endoperoxides OZ78 and MT04 (Publications)
The synthetic peroxides OZ78 and MT04 recently emerged as fasciocidal drug candidates. However, the effect of iron on fasciocidal activity and hepatocellular toxicity of these compounds is unknown. We
Animal-assisted therapy for patients in a minimally conscious state: a randomized two treatment multi-period crossover trial (Publications)
OBJECTIVE: To investigate if animal-assisted therapy (AAT) leads to higher consciousness in patients in a minimally conscious state during a therapy session, measured via behavioral reactions, heart r
Research and implementation lessons learned from a youth-targeted digital health randomized controlled trial (the ARMADILLO Study) (Publications)
BACKGROUND: Evidence is lacking on the efficacy of sexual and reproductive health (SRH) communication interventions for youth (aged 15-24 years), especially from low- and middle-income countries. Ther
Case report: human subcutaneous sparganosis in a Thai migrant (Publications)
Human sparganosis is a cestode infection which is neglected as a differential diagnosis outside endemic countries. Diagnosis and therapy may be challenging depending on the clinical presentation and a
State of deworming coverage and equity in low-income and middle-income countries using household health surveys: a spatiotemporal cross-sectional... (Publications)
BACKGROUND: Mass deworming against soil-transmitted helminthiasis, which affects 1 billion of the poorest people globally, is one of the largest public health programmes for neglected tropical disease
Multi-center screening of the Pathogen Box collection for schistosomiasis drug discovery (Publications)
BACKGROUND: Over the past five years, as a public service to encourage and accelerate drug discovery for diseases of poverty, the Medicines for Malaria Venture (MMV) has released box sets of 400 compo