Effects of a partially supervised conditioning program in cystic fibrosis: an international multicenter, randomized controlled trial (ACTIVATE-CF) (Publications)
Rationale: The long-term effects of vigorous physical activity (PA) on lung function in cystic fibrosis are unclear. Objectives: To evaluate effects of a 12-month partially supervised PA intervention
Multi-insecticide resistant malaria vectors in the field remain susceptible to malathion, despite the presence of <em>Ace1</em> point mutations (Publications)
Insecticide resistance in Anopheles mosquitoes is seriously threatening the success of insecticide-based malaria vector control. Surveillance of insecticide resistance in mosquito populations and iden
Aberrant stromal tissue factor localisation and mycolactone-driven vascular dysfunction, exacerbated by IL-1β, are linked to fibrin formation in... (Publications)
Buruli ulcer (BU) is a neglected tropical disease caused by subcutaneous infection with Mycobacterium ulcerans and its exotoxin mycolactone. BU displays coagulative necrosis and widespread fibrin depo
<em>Plasmodium falciparum</em> parasite prevalence in East Africa: updating data for malaria stratification (Publications)
The High Burden High Impact (HBHI) strategy for malaria encourages countries to use multiple sources of available data to define the sub-national vulnerabilities to malaria risk, including parasite pr
Detection of asymptomatic malaria in Asian countries: a meta-analysis of diagnostic accuracy (Publications)
Background: Achieving malaria elimination requires the targeting of the human reservoir of infection, including those patients with asymptomatic infection. The objective was to synthesise evidence on
Genomic analyses of human adenoviruses unravel novel recombinant genotypes associated with severe infections in pediatric patients (Publications)
Human adenoviruses (HAdVs) are highly contagious pathogens of clinical importance, especially among the pediatric population. Studies on comparative viral genomic analysis of cases associated with sev
Cultural practices during pregnancy and birth among the Giriama community in coastal Kenya: a qualitative study (Publications)
Pregnancy and childbirth are almost universally associated with culturally based ceremonies and rituals. Although the importance of giving birth in a healthcare facility is recognized among the Giriam
Failure to return pillbox is a predictor of being lost to follow-up among people living with HIV on antiretroviral therapy in rural Tanzania (Publications)
OBJECTIVES: Pill count is used to assess drug adherence in people living with HIV (PLHIV). Carrying a pillbox is associated with fear of concealment and stigma and might indicate poor adherence and pr
Assessment of FDA-approved drugs against <em>Strongyloides ratti in vitro</em> and <em>in vivo</em> to identify potentially active drugs against... (Publications)
BACKGROUND: Infections with Strongyloides stercoralis belong to the most neglected helminth diseases, and research and development (R&D) efforts on novel drugs are inadequate. METHODS: A commercially