Prisons as ecological drivers of fitness-compensated multidrug-resistant <em>Mycobacterium tuberculosis</em> (Publications)
Multidrug-resistant tuberculosis (MDR-TB) accounts for one third of the annual deaths due to antimicrobial resistance(1). Drug resistance-conferring mutations frequently cause fitness costs in bacteri
Associations between infection intensity categories and morbidity prevalence in school-age children are much stronger for <em>Schistosoma haematobium... (Publications)
BACKGROUND: World Health Organization (WHO) guidelines for measuring global progress in schistosomiasis control classify individuals with Schistosoma spp. infections based on the concentration of excr
An antigen capture assay for the detection of mycolactone, the polyketide toxin of <em>Mycobacterium ulcerans</em> (Publications)
Mycolactone is a cytotoxin responsible for most of the chronic necrotizing pathology of Mycobacterium ulcerans disease (Buruli ulcer). The polyketide toxin consists of a 12-membered lactone ring with
Caesarean sections and health financing: a global analysis (Publications)
OBJECTIVES: The objective of this study is to explore the association of health financing indicators with the proportion of births by caesarean section (CS) across countries. DESIGN: Ecological cross-
Mortality from drug-resistant tuberculosis in high-burden countries comparing routine drug susceptibility testing with whole-genome sequencing: a... (Publications)
Background: Drug resistance threatens global tuberculosis control. We aimed to examine mortality in patients with tuberculosis from high-burden countries, according to concordance or discordance of re
Early whole blood transcriptional responses to radiation-attenuated <em>Plasmodium falciparum</em> sporozoite vaccination in malaria naive and malaria... (Publications)
BACKGROUND: Vaccination with radiation-attenuated Plasmodium falciparum sporozoites is known to induce protective immunity. However, the mechanisms underlying this protection remain unclear. In this w