Cell biological characterization of the malaria vaccine candidate trophozoite exported protein 1 (Publications)
In a genome-wide screen for alpha-helical coiled coil motifs aiming at structurally defined vaccine candidates we identified PFF0165c. This protein is exported in the trophozoite stage and was named a
How much remains undetected? Probability of molecular detection of human <em>Plasmodia</em> in the field (Publications)
BACKGROUND: In malaria endemic areas, most people are simultaneously infected with different parasite clones. Detection of individual clones is hampered when their densities fluctuate around the detec
Clonal waves of <em>Neisseria</em> colonisation and disease in the African meningitis belt: eight- year longitudinal study in Northern Ghana (Publications)
BACKGROUND: The Kassena-Nankana District of northern Ghana lies in the African "meningitis belt" where epidemics of meningococcal meningitis have been reoccurring every eight to 12 years for the last
Diagnostic accuracy of Kato-Katz and FLOTAC for assessing anthelmintic drug efficacy (Publications)
BACKGROUND: Sensitive diagnostic tools are required for an accurate assessment of prevalence and intensity of helminth infections in areas undergoing regular deworming, and for monitoring anthelmintic
Patterns and risk factors of helminthiasis and anemia in a rural and a peri-urban community in Zanzibar, in the context of helminth control programs (Publications)
BACKGROUND: The control of helminth infections and prevention of anemia in developing countries are of considerable public health importance. The purpose of this study was to determine patterns and ri
Modern geographical reconnaissance of target populations in malaria elimination zones (Publications)
ABSTRACT: BACKGROUND: Geographical Reconnaissance (GR) operations using Personal Digital Assistants (PDAs) and Global Positioning Systems (GPS) have been conducted in the elimination provinces of Temo
Routine delivery of artemisinin-based combination treatment at fixed health facilities reduces malaria prevalence in Tanzania: an observational study (Publications)
ABSTRACT: BACKGROUND: Artemisinin-based combination therapy (ACT) has been promoted as a means to reduce malaria transmission due to their ability to kill both asexual blood stages of malaria parasite
Varying efficacy of intermittent preventive treatment for malaria in infants in two similar trials: public health implications (Publications)
BACKGROUND: Intermittent preventive treatment (IPTi) with sulphadoxine-pyrimethamine (SP) in infants resulted in different estimates of clinical malaria protection in two trials that used the same pro
Exposure to moderate air pollution during late pregnancy and cord blood cytokine secretion in healthy neonates (Publications)
BACKGROUND/OBJECTIVES: Ambient air pollution can alter cytokine concentrations as shown in vitro and following short-term exposure to high air pollution levels in vivo. Exposure to pollution during la