Use of whole genome sequencing to determine the microevolution of <em>Mycobacterium tuberculosis</em> during an outbreak (Publications)
RATIONALE: Current tools available to study the molecular epidemiology of tuberculosis do not provide information about the directionality and sequence of transmission for tuberculosis cases occurring
<em>Strongyloides ratti</em>: in vitro and in vivo activity of tribendimidine (Publications)
BACKGROUND: Strongyloidiasis is a truly neglected tropical disease, but its public health significance is far from being negligible. At present, only a few drugs are available for the treatment and co
Impact of health research capacity strengthening in low- and middle-income countries: the case of WHO/TDR programmes (Publications)
BACKGROUND: Measuring the impact of capacity strengthening support is a priority for the international development community. Several frameworks exist for monitoring and evaluating funding results and
Ambient air pollution and the progression of atherosclerosis in adults (Publications)
BACKGROUND: Cross-sectional studies suggest an association between exposure to ambient air pollution and atherosclerosis. We investigated the association between outdoor air quality and progression of
Task shifting to non-physician clinicians for integrated management of hypertension and diabetes in rural Cameroon: a programme assessment at two... (Publications)
ABSTRACT: BACKGROUND: The burden of non-communicable chronic diseases, such as hypertension and diabetes, increases in sub-Saharan Africa. However, the majority of the rural population does still not
Guidance for evidence-informed policies about health systems: assessing how much confidence to place in the research evidence (Publications)
In the third paper in a three-part series on health systems guidance, Simon Lewin and colleagues explore the challenge of assessing how much confidence to place in evidence on health systems intervent
Quantifying behavioural interactions between humans and mosquitoes: Evaluating the protective efficacy of insecticidal nets against malaria... (Publications)
ABSTRACT: BACKGROUND: African malaria vectors bite predominantly indoors at night so sleeping under an Insecticide-Treated Net (ITN) can greatly reduce malaria risk. Behavioural adaptation by mosquito
Efficacy of sulfadoxine-pyrimethamine in Tanzania after two years as first-line drug for uncomplicated malaria: assessment protocol and implication... (Publications)
BACKGROUND: Systematic surveillance for resistant malaria shows high level of resistance of Plasmodium falciparum to sulfadoxine-pyrimethamine (SP) across eastern and southern parts of Africa. This st
Behavioural determinants of gene flow in malaria vector population: <em>Anopheles gambiae</em> males select large females as mates (Publications)
BACKGROUND: Plasmodium-refractory mosquitoes are being rapidly developed for malaria control but will only succeed if they can successfully compete for mates when released into the wild. Pre-copulator