The elusive meningococcal meningitis serogroup: a systematic review of serogroup B epidemiology (Publications)
BACKGROUND: Invasive meningococcal disease (IMD), is a widely distributed, complex human disease affecting all age categories. The causative agent, Neisseria meningitidis, is spread through aerosol re
Advancing drug innovation for neglected diseases-criteria for lead progression (Publications)
The current drug R&D pipeline for most neglected diseases remains weak, and unlikely to support registration of novel drug classes that meet desired target product profiles in the short term. This cal
Determinants of the cost-effectiveness of intermittent preventive treatment for malaria in infants and children (Publications)
BACKGROUND: Trials of intermittent preventive treatment in infants (IPTi) and children (IPTc) have shown promising results in reducing malaria episodes but with varying efficacy and cost-effectiveness
Schistosomiasis, soil-transmitted helminthiasis, and sociodemographic factors influence quality of life of adults in Côte d'Ivoire (Publications)
BACKGROUND: Burden of disease estimates are widely used for priority setting in public health and disability-adjusted life years are a powerful "currency" nowadays. However, disability weights, which
Molecular surveillance of drug resistance through imported isolates of <em>Plasmodium falciparum</em> in Europe (Publications)
BACKGROUND: Results from numerous studies point convincingly to correlations between mutations at selected genes and phenotypic resistance to antimalarials in Plasmodium falciparum isolates. In order
Cancer risk in adolescents and young adults living with HIV in South Africa: a nationwide cohort study (Publications)
BACKGROUND: Literature on cancer in adolescents and young adults (AYA; aged 15-24 years) living with HIV is scarce. We studied cancer incidence in AYA living with HIV in South Africa between 2004 and
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation (Publications)
Characterizing genetic influences on DNA methylation (DNAm) provides an opportunity to understand mechanisms underpinning gene regulation and disease. In the present study, we describe results of DNAm