In-hospital safety in field conditions of nifurtimox eflornithine combination therapy (NECT) for <em>T.b. gambiense</em> sleeping sickness (Publications)
BACKGROUND: Trypanosoma brucei (T.b.) gambiense Human African trypanosomiasis (HAT; sleeping sickness) is a fatal disease. Until 2009, available treatments for 2(nd) stage HAT were complicated to use,
Phylogenomics of ligand-gated ion channels predicts monepantel effect (Publications)
The recently launched veterinary anthelmintic drench for sheep (Novartis Animal Health Inc., Switzerland) containing the nematocide monepantel represents a new class of anthelmintics: the amino-aceton
Evaluating the effectiveness of IPTi on malaria using routine health information from sentinel health centres in southern Tanzania (Publications)
BACKGROUND: Intermittent preventive treatment of malaria in infants (IPTi) consists of the administration of a treatment dose of sulphadoxine-pyrimethamine (SP) at the time of routine vaccinations. Th
Rapid urban malaria appraisal (RUMA) I: Epidemiology of urban malaria in Ouagadougou (Publications)
BACKGROUND: Rapid urbanization in sub-Saharan Africa has a major impact on malaria epidemiology. While much is known about malaria in rural areas in Burkina Faso, the urban situation is less well unde
Rapid urban malaria appraisal (RUMA) in sub-Saharan Africa (Publications)
BACKGROUND: The rapid urban malaria appraisal (RUMA) methodology aims to provide a cost-effective tool to conduct rapid assessments of the malaria situation in urban sub-Saharan Africa and to improve
No <em>Paragonimus</em> in high-risk groups in Côte d'Ivoire, but considerable prevalence of helminths and intestinal protozoon infections (Publications)
ABSTRACT: BACKGROUND: Paragonimiasis is a neglected tropical disease caused by an infection with lung flukes that is transmitted through the consumption of undercooked crabs. The disease is often conf
Isothermal microcalorimetry, a new tool to monitor drug action against <em>Trypanosoma brucei</em> and <em>Plasmodium falciparum</em> (Publications)
Isothermal microcalorimetry is an established tool to measure heat flow of physical, chemical or biological processes. The metabolism of viable cells produces heat, and if sufficient cells are present