3D QSAR on a library of heterocyclic diamidine derivatives with antiparasitic activity (Publications)
African trypanosomes, Trypanosoma brucei rhodesiense (TBR) and Trypanosoma brucei gambiense (TBG), affect hundreds of thousands of lives in tropical regions of the world. The toxicity of the diamidine
Pharmacophore model for pentamidine analogs active against <em>Plasmodium falciparum</em> (Publications)
Pentamidine and its analogs constitute a class of compounds that are known to be active against Plasmodium falciparum, which causes the most dangerous malarial infection. Malaria is a widespread disea
Community effectiveness of intermittent preventive treatment for infants (IPTi) in rural southern Tanzania (Publications)
Intermittent preventive treatment of malaria in infants (IPTi) with sulphadoxine-pyrimethamine shows evidence of efficacy in individually randomized, controlled trials. In a large-scale effectiveness
Effect of large-scale social marketing of insecticide-treated nets on child survival in rural Tanzania (Publications)
BACKGROUND: Insecticide-treated nets have proven efficacy as a malaria-control tool in Africa. However, the transition from efficacy to effectiveness cannot be taken for granted. We assessed coverage
Gender and community views of stigma and tuberculosis in rural Maharashtra, India (Publications)
Stigma associated with tuberculosis (TB) is often regarded as a barrier to health seeking and a cause of social suffering. Stigma studies are typically patient-centred, and less is known about the vie
Bovine tuberculosis: an old disease but a new threat to Africa (Publications)
Bovine tuberculosis (TB) is a disease characterised by progressive development of specific granulomatous lesions or tubercles in lung tissue, lymph nodes or other organs. Mycobacterium bovis is the ca
Deliberate self-harm and suicide by pesticide ingestion in the Sundarban region, India (Publications)
OBJECTIVE: To examine the clinical epidemiology, including case fatality and determinants of self-harm in six island blocks of the Sundarban region of West Bengal, India. METHODS: We examined the clin