Effectiveness of dog rabies vaccination programmes: comparison of owner-charged and free vaccination campaigns (Publications)
We investigated the percentage of dogs that could be vaccinated against rabies by conducting a pilot campaign in N'Djamena, Chad. Owners were charged US$4.13 per dog vaccinated, and 24% of all dogs in
The structure and antimalarial activity of dispiro-1,2,4,5-tetraoxanes derived from (+)-dihydrocarvone (Publications)
An unsaturated dispiro 1,2,4,5-tetraoxane formed by peroxidation of (+)-dihydrocarvone was converted into four structurally diverse derivatives. X-ray crystallographic analysis shows that the structur
Comparative antimalarial activities of six pairs of 1,2,4,5-tetraoxanes (peroxide dimers) and 1,2,4,5,7,8-hexaoxonanes (peroxide trimers) (Publications)
Six tetraoxanes had 50% inhibitory concentrations in the range of 10 to 100 ng/ml against Plasmodium falciparum, whereas the corresponding hexaoxonanes had minimal antimalarial activity. The lack of i
Seroprevalences and local variation of human and livestock brucellosis in two villages in Gharbia Governorate, Egypt (Publications)
This study aimed at assessing the epidemiology of brucellosis among both human and livestock populations in an endemic area in Egypt. A cross-sectional survey was conducted in two villages, where 616
Okundoperoxide, a bicyclic cyclofarnesylsesquiterpene endoperoxide from <em>Scleria striatinux</em> with antiplasmodial activity (Publications)
Okundoperoxide (1) was isolated by bioassay-guided fractionation of extracts from Scleria striatinux (syn. S. striatonux). The compound contains a cyclic endoperoxide structural moiety and possesses m
Prenatal exposure to a farm environment modifies atopic sensitization at birth (Publications)
BACKGROUND: Previous cross-sectional surveys have suggested that maternal exposure to animal sheds during pregnancy exerted a protective effect on atopic sensitization in children lasting until school
The structure-activity relationship of the antimalarial ozonide arterolane (OZ277) (Publications)
The structure and stereochemistry of the cyclohexane substituents of analogues of arterolane (OZ277) had little effect on potency against Plasmodium falciparum in vitro. Weak base functional groups we