Global phylogenomic analysis of nonencapsulated <em>Streptococcus pneumoniae</em> reveals a deep-branching classic lineage that is distinct from... (Publications)
The surrounding capsule of Streptococcus pneumoniae has been identified as a major virulence factor and is targeted by pneumococcal conjugate vaccines (PCV). However, nonencapsulated Streptococcus pne
Zoonotic <em>Mycobacterium bovis</em> - induced tuberculosis in humans (Publications)
We aimed to estimate the global occurrence of zoonotic tuberculosis (TB) caused by Mycobacterium bovis or M. caprae infections in humans by performing a multilingual, systematic review and analysis of
Essential evidence for guiding health system priorities and policies: anticipating epidemiological transition in Africa (Publications)
Background: Despite indications that infection-related mortality in sub-Saharan Africa may be decreasing and the burden of non-communicable diseases increasing, the overwhelming reality is that health
Estimating population and livestock density of mobile pastoralists and sedentary settlements in the south-eastern Lake Chad area (Publications)
Mobile pastoralists provide major contributions to the gross domestic product in Chad, but little information is available regarding their demography. The Lake Chad area population is increasing, resu
A mechanistic paradigm for broad-spectrum antivirals that target virus-cell fusion (Publications)
LJ001 is a lipophilic thiazolidine derivative that inhibits the entry of numerous enveloped viruses at non-cytotoxic concentrations (IC50?0.5 µM), and was posited to exploit the physiological differen
Structure-activity relationship study of sesquiterpene lactones and their semi-synthetic amino derivatives as potential antitrypanosomal products (Publications)
Sesquiterpene lactones (STLs) are natural products that have potent antitrypanosomal activity in vitro and, in the case of cynaropicrin, also reduce parasitemia in the murine model of trypanosomiasis.
Water-related parasitic diseases in China (Publications)
Water-related parasitic diseases are directly dependent on water bodies for their spread or as a habitat for indispensable intermediate or final hosts. Along with socioeconomic development and improve
Revising the WHO verbal autopsy instrument to facilitate routine cause-of-death monitoring (Publications)
Objective : Verbal autopsy (VA) is a systematic approach for determining causes of death (CoD) in populations without routine medical certification. It has mainly been used in research contexts and in
Air pollution and mortality in seven million adults: the Dutch Environmental Longitudinal Study (DUELS) (Publications)
BACKGROUND: Long-term exposure to air pollution has been associated with mortality in urban cohort studies. Few studies have investigated this association in large scale population registries, includi
Cultural epidemiology of pandemic influenza in urban and rural Pune, India: a cross-sectional, mixed-methods study (Publications)
OBJECTIVE: To identify and compare sociocultural features of pandemic influenza with reference to illness-related experience, meaning and behaviour in urban and rural areas of India. DESIGN: Cross-sec