AAA proteases of mitochondria: quality control of membrane proteins and regulatory functions during mitochondrial biogenesis (Publications)
An ubiquitous and conserved proteolytic system regulates the stability of mitochondrial inner membrane proteins. Two AAA proteases with catalytic sites at opposite membrane surfaces form a membrane-in
Single nucleotide polymorphism typing of <em>Mycobacterium ulcerans</em> reveals focal transmission of Buruli ulcer in a highly endemic region of... (Publications)
Buruli ulcer (BU) is an emerging necrotizing disease of the skin and subcutaneous tissue caused by Mycobacterium ulcerans. While proximity to stagnant or slow flowing water bodies is a risk factor for
Optimized DNA preparation from mycobacteria (Publications)
Extraction of genomic DNA from mycobacteria requires special consideration because (i) many mycobacterial species exhibit extremely slow growth, and thus produce only small amounts of starting materia
Risk factors for Buruli ulcer in Ghana - a case control study in the Suhum-Kraboa-Coaltar and Akuapem south districts of the eastern region (Publications)
BACKGROUND: Buruli ulcer (BU) is a skin disease caused by Mycobacterium ulcerans. Its exact mode of transmission is not known. Previous studies have identified demographic, socio-economic, health and
Evolution of two distinct phylogenetic lineages of the emerging human pathogen <em>Mycobacterium ulcerans</em> (Publications)
ABSTRACT: BACKGROUND: Comparative genomics has greatly improved our understanding of the evolution of pathogenic mycobacteria such as Mycobacterium tuberculosis. Here we have used data from a genome m