MalCommit - Understanding Sexual Commitment and Early Differentiation of Malaria Transmission Stages (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/malcommit-understanding-sexual-commitment-and-early-differentiation-of-malaria-transmission-stages
The project aims to understand the processes responsible for the differentiation of asexual malaria blood stage parasites into sexual forms. The anticipated results may open up new avenues for the development
The useful life of bednets for malaria control in Tanzania: Attrition, Bioefficacy, Chemistry, Damage and Insecticide Resistance. (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/the-useful-life-of-bednets-for-malaria-control-in-tanzania-attrition-bioefficacy-chemistry-damage-and-insecticide-resistance
life of bednets for malaria control in Tanzania: Attrition, Bioefficacy, Chemistry, Damage and insecticide Resistance. Long-Lasting Insecticidal Nets (LLINs) are the front line malaria vector control tool [...] practice for the maintenance of high and cost-effective coverage and to maximise current gains in malaria control. We will make the data available to stakeholders including NMCP and their collaborators:
Understanding heterogeneities in the epidemiology of malaria in Papua New Guinea (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/understanding-heterogeneities-in-the-epidemiology-of-malaria-in-papua-new-guinea
Background Malaria has been endemic across most parts of Papua New Guinea (PNG) at endemicity levels comparable to sub-Saharan Africa. The National Malaria Control Program (NMCP) has managed to substantially [...] impact of malaria control interventions and underlying secular trends. Drivers of change, and reasons for differences between sites will be investigated. 2) Geo-referenced data on clinical malaria cases will [...] ongoing mathematical modelling of heterogeneities in malaria dynamics at...
Estimating the extent, patterns and consequences of heterogeneity in malaria dynamics (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/estimating-the-extent-patterns-and-consequences-of-heterogeneity-in-malaria-dynamics
Background The uneven distribution of malaria is apparent on a small scale, within a single study site or even cluster of houses. Transmission varies with mosquito densities related to breeding sites, [...] relatively high transmission, have been identified. Heterogeneity has implications for many areas of malaria epidemiology, not least the design of intervention strategies. Whilst the existence of heterogeneity [...] heterogeneity, and inform the design of control strategies and the...
Combining sociological, economic and epidemiological evidence to target malaria interventions in Papua New Guinea and beyond (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/combining-sociological-economic-and-epidemiological-evidence-to-target-malaria-interventions-in-papua-new-guinea-and-beyond
interventions. However, current recommendations focus exclusively on stratification by malaria risk. Yet, malaria is multi-factorial and the impact of interventions in a given setting also depends on [...] conceptual framework for a multi-dimensional malaria stratification beyond mere epidemiological indicators. Papua New Guinea (PNG) with its complex malaria epidemiology serves as a model country. Project [...] To improve the (cost-) effectiveness of malaria control and accelerate progress...
Environmental, Social, Economic and Health Impact Assessment (ESHIA) for a Field Study of a Self-Limiting Nondrive Strain of Genetically Modified... (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/environmental-social-economic-and-health-impact-assessment-eshia-for-a-field-study-of-a-self-limiting-nondrive-strain-of-genetically-modified-mosquitoes-on-behalf-of-target-malaria
Genetically modified mosquitoes (GMMs) represent great potential for malaria control in the future. Target Malaria – a vector control research alliance based at the Imperial College in London – aims to [...] develop genetic technologies to modify mosquitoes with the ultimate goal to reduce malaria transmission. Target Malaria uses a three-phased approach in this 170-million project funded by the Bill and Melinda
The beauty of disease modelling (Page)
https://www.swisstph.ch/fr/impact-stories/the-beauty-of-disease-modelling
modelling for malaria vaccines? Similar to vaccines, we often ask questions about how we can can reduce the burden of disease. Many of the malaria models that were created to look at malaria vaccines have [...] modelling here is not just estimating the impact of the malaria vaccine or a single intervention but we can ask a whole range of questions about malaria disease dynamics, intervention packages and drug resistance [...] n packages for different national malaria control programmes....
“It is a privilege to be able to bring science to the bedside” (Page)
https://www.swisstph.ch/fr/impact-stories/it-is-a-privilege-to-be-able-to-bring-science-to-the-bedside
test a drug for a neglected disease such as malaria, the trial can become more complex, because we have to go where the malaria patients are, i.e., to a malaria-endemic country such as the DRC. Such sites [...] very effective and affordable medicines for malaria? Yes, artemisinin-based combination therapies (ACTs) are still the standard of care for treating malaria and remain very effective. However, we are seeing [...] in the fight against malaria? What is unique about Swiss TPH is that we work...