Genetic composition of Plasmodium falciparum infections in Zanzibar, travel and transmission: a follow-up to the RADZEC study (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/genetic-composition-of-plasmodium-falciparum-infections-in-zanzibar-travel-and-transmission-a-follow-up-to-the-radzec-study
investigations, we will analyse travel patterns of malaria patients and their household contacts to investigate associations of particular travel patterns with malaria infection status in general, and infection [...] Travel between Zanzibar and mainland Tanzania is likely to contribute substantially to the malaria case load on the islands of Zanzibar. In this study, we will investigate the genetic composition of P [...] in particular. This will be complemented by modeling of the improtance of...
Further development of simulations of Plasmodium falciparum interventions and their integration with the needs of stakeholders II (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/further-development-of-simulations-of-plasmodium-falciparum-interventions-and-their-integration-with-the-needs-of-stakeholders-ii
models for predicting the effects of different malaria interventions. It is centered on contributions to the multi-group Bill and Melinda Gates Foundation Malaria Modeling Consortium (MMC). Specific areas [...] e of malaria, of residual transmission, of prioritization and targeting of interventions, and modeling of surveillance-response systems. One important tool used in the project is the OpenMalaria open source [...] including analyses of health systems, pharmacodynamics, and entomological...
Analysis and mapping of prospective sources of funding for additional contributions to MEMTI (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/analysis-and-mapping-of-prospective-sources-of-funding-for-additional-contributions-to-memti
The Global Fund to Fight AIDS, Tuberculosis and Malaria set aside funding to incentivize the acceleration of efforts towards elimination of malaria in four countries in the Asia-Pacific region: Papua New [...] New Guinea, Solomon Islands, Vanuatu and Timor-Leste. This "Malaria Elimination in Melanesia and Timor-Leste Initiative" (MEMTI) is additional to Global Fund country funding allocations and is intended [...] development partners. Regarding the identification of all sources of funding for...
Analysis and mapping of prospective sources of funding for additional contributions to MEMTI (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/analysis-and-mapping-of-prospective-sources-of-funding-for-additional-contributions-to-memti
The Global Fund to Fight AIDS, Tuberculosis and Malaria set aside funding to incentivize the acceleration of efforts towards elimination of malaria in four countries in the Asia-Pacific region: Papua New [...] New Guinea, Solomon Islands, Vanuatu and Timor-Leste. This "Malaria Elimination in Melanesia and Timor-Leste Initiative" (MEMTI) is additional to Global Fund country funding allocations and is intended [...] development partners. Regarding the identification of all sources of funding for...
MATIAS (Page)
https://www.swisstph.ch/fr/about/med/medicines-implementation-research/matias
for treatment of severe malaria caused by Plasmodium falciparum . These results with high quality evidence led to a change in the WHO guidelines for the treatment of severe malaria in children and adults [...] Key Project | MATIAS Treatment of Severe Malaria with Injectable Artesunate Implementation Non-Controlled Longitudinal Observational Study to Support Artesunate Introduction in the Democratic Republic [...] the Congo (DRC) In 2010, the AQUAMAT study demonstrated that, in children, the...
Clinical Immunology (Page)
https://www.swisstph.ch/fr/about/mpi/clinical-immunology
Nele von Planta Selected Projects EGMVI - Equatorial Guinea Malaria Vaccine Initiative MAL067 - MAL067 - Studies towards understanding RTS,S malaria vaccine induced protection SNF_FP_modelling - Multi-scale [...] development of novel drugs against malaria. Lancet Infect Dis . 2022;22:753-754. DOI: 10.1016/S1473-3099(21)00679-4 Daubenberger C. Assessment of experimental malaria vaccine induced protection in pre-exposed [...] well as host factors elicited by subunit and whole parasite vaccines...
CALINA Study Shows Positive Efficacy and Safety Data for a Novel Treatment for Small Babies (News)
https://www.swisstph.ch/fr/news/news-detail-1/news/calina-study-shows-positive-efficacy-and-safety-data-for-a-novel-treatment-for-babies
Malaria exerts a massive burden on public health across the world, particularly in Africa. Huge strides have been made in recent decades in the treatment of malaria. However, to date, little data has been [...] – babies less than 5 kg. Closing the malaria treatment gap The CALINA study is led by Novartis, with the scientific and financial support of Medicines for Malaria Venture (MMV), and as part of the PAMAfrica [...] in babies under 5kg. Infants under 5 kg can be affected by placental malari...
Medicines Implementation Research | Research at Swiss TPH (Page)
https://www.swisstph.ch/fr/about/med/miru
Treatment of severe Malaria The serious disease malaria is a major burden in tropical and subtropical countries. Although great efforts have been made to control and eliminate malaria, more than 400,000 [...] Rectal Artesunate for Malaria Many children suffering from severe malaria live in poor rural communities with no access to health care. Where parenteral treatment of severe malaria is not available, the [...] Artesunate to Treat Severe Malaria The serious disease malaria is a high burden in...
Assessment of Anopheles stephensi surveillance needs, practices and priorities in Global Fund-supported countries in the Horn of Africa (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/assessment-of-anopheles-stephensi-surveillance-needs-practices-and-priorities-in-global-fund-supported-countries-in-the-horn-of-africa
efficient malaria vector, particularly in urban environments, appearing to quickly adapting itself to the local environment and surviving extremely high temperatures during the dry season, when malaria transmission [...] across sub-Saharan Africa, led the World WHO Global Malaria Programme to publish a vector alert noting the major potential threat the vector poses to malaria control and elimination in sub-Saharan Africa. The [...] In recent years, An. stephensi , an efficient urban malaria...
Nicolas Brancucci Appointed Professor at the University of Basel (News)
https://www.swisstph.ch/fr/news/news-detail-1/news/nicolas-brancucci-appointed-professor-at-the-university-of-basel
on the process of malaria transmission stage formation. Brancucci will lead a new unit at Swiss TPH called "Malaria Host Interactions". The unit studies the way in which the malaria parasite P. falciparum [...] Basel, where he investigated epigenetic mechanisms controlling antigenic variation of the human malaria parasite Plasmodium falciparum . He then worked as a postdoctoral fellow in Boston (Harvard T. H