Swiss TPH and PNGIMR: Strengthening a 30-Year Partnership (News)
https://www.swisstph.ch/fr/news/news-detail-1/news/swiss-tph-and-pngimr-strengthening-a-30-year-partnership
National Malaria Control Programme, providing evidence of the impact of large-scale malaria control efforts. In addition, Swiss TPH is involved in research to identify drivers of ongoing malaria transmission [...] Research (PNGIMR) have a long and successful history of collaboration, primarily in the field of malaria, with a strong emphasis on capacity building in Papua New Guinea (PNG). In the last 10 years, 11 [...] transmission and in molecular investigations of the complex local malaria...
Parasite Chemotherapy (Page)
https://www.swisstph.ch/fr/about/mpi/parasite-chemotherapy
African trypanosomes and malaria) and molecular approaches to drug action and resistance. The PCU works closely with product development partnerships such as the Medicines for Malaria Venture (MMV), DNDi or [...] 20 years of experience in assay development and drug efficacy testing for the causative agents of malaria (Plasmodium spp.), African sleeping sickness (Trypanosoma brucei), Chagas disease (T. cruzi), le [...] clinical candidates, including fexinidazole for human African trypanosomiasis...
Vector Modelling - AnophelesModel R Package (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/vector-modelling-anophelesmodel-r-package
for the entomological and vector control components of more complex models of malaria transmission dynamics such as OpenMalaria . Mosquito distribution and human behavior vary across geographical settings [...] Package to interface mosquito bionomics, human exposure and intervention effects with models of malaria intervention impact. The package contains an in-built entomological model of the mosquito feeding [...] n parameters. The different types of data have been extracted from field studies...
SNSF Professorship Awarded to Melissa Penny (News)
https://www.swisstph.ch/fr/news/news-detail-1/news/snsf-professorship-awarded-to-melissa-penny
medicines and vaccines more efficient, ensuring innovation and tailoring of these interventions towards malaria and disease elimination.” Melissa Penny has been a project leader at Swiss TPH since 2013, focusing [...] focusing on developing mathematical models that provide quantitative evidence to support malaria control and elimination decisions. She recently led a multi-institute collaboration to provide evidence to the [...] Organization (WHO) and other institutions on the public health...
Mathematical modelling to examine disease, control measures, vaccine interactions and resistance to guide public health and disease elimination... (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/mathematical-modelling-to-examine-disease-control-measures-vaccine-interactions-and-resistance-to-guide-public-health-and-disease-elimination-strategies
resistance to disease interventions. We address two important pathogens: malaria and SARS-Cov-2. As we get closer to eliminating malaria and other diseases, preventing diseases from evolving resistance to response [...] detailed parasite models, mosquito-to-human transmission models and adapt individual-level models for malaria. We will also adapt models of SARS-CoV-2 to examine the emergence of vaccine-resistant COVID variants [...] pathogens. We will examine resistance to vaccines, drugs and...
Mathematical modelling to examine disease, control measures, vaccine interactions and resistance to guide public health and disease elimination... (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/mathematical-modelling-to-examine-disease-control-measures-vaccine-interactions-and-resistance-to-guide-public-health-and-disease-elimination-strategies
resistance to disease interventions. We address two important pathogens: malaria and SARS-Cov-2. As we get closer to eliminating malaria and other diseases, preventing diseases from evolving resistance to response [...] detailed parasite models, mosquito-to-human transmission models and adapt individual-level models for malaria. We will also adapt models of SARS-CoV-2 to examine the emergence of vaccine-resistant COVID variants [...] pathogens. We will examine resistance to vaccines, drugs and...
R. Geigy Award 2020 goes to Tobias Schindler (News)
https://www.swisstph.ch/fr/news/news-detail-1/news/r-geigy-award-2020-goes-to-tobias-schindler
controlled malaria infection. The test individuals were injected with infectious malaria pathogens, or so-called sporozoites. They were then treated for the disease immediately after the malaria parasites [...] diseases is not common in Africa, as patients with a fever are still routinely treated only for malaria. Together with partners from the Ifakara Health Institute (IHI), Tobias Schindler, Postdoctoral [...] Collaborator at Swiss TPH, has developed a molecular diagnostic platform for the...
WHO TVC (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/who-tvc
Increasing coverage of malaria vector control interventions globally has led to significant reductions in disease burden. However due to its high recurrent cost, there is a need to determine if and when [...] reduced. We conduct literature reviews and simulate a mathematical model of Plasmodium falciparum malaria epidemiology to determine the impact of scaling back vector control on transmission and disease.
Visual Analysis of Long Lasting Insecticidal Nets to Maximise Universal Access (Projects)
https://www.swisstph.ch/fr/projects/project-detail/project/visual-analysis-of-long-lasting-insecticidal-nets-to-maximise-universal-access
vital in reducing the malaria burden among children over the last 20 years. Reductions have stagnated and resources available for control are half what is needed to meet malaria control milestones. Standard [...] between products, influencing their value-for-money. This project will deliver information to National Malaria Control Programs (NMCP) that enables them to 1) select durable and cost-effective LLINs to buy, 2) [...] NMCP=medium to select the best LLINs for their setting to optimize the...
Molecular Immunology | Research at Swiss TPH (Page)
https://www.swisstph.ch/fr/about/med/molecular-immunology
ch Key Projects Malaria P. falciparum : developing a synthetic subunit candidate vaccine Malaria is one of the most serious infectious diseases of humans. New approaches to combat malaria are urgently needed [...] efficacy of therapeutic interventions. This research focuses primarily on three infectious diseases: malaria due to Plasmodium falciparum, bacterial meningitis caused by Neisseria meningitides and Streptococcus [...] developing synthetic peptide structures that induce cross-reactive...