Effects of vector-control interventions on changes in risk of malaria parasiotaemia in sub-Saharan Africa: a spatial and temporal analysis (Publications)
episodes and deaths due to malaria have been mainly associated with the expansion of vector-control measures, such as insecticide-treated bednets and indoor residual spraying. Malaria indicator surveys gather [...] gather information about key malaria indicators through national representative household surveys. We aimed to estimate changes in risk of malaria parasitaemia at high spatial resolution in sub-Saharan Africa [...] that had publicly available data from two malaria indicator or...
Metabolic profiling framework for discovery of candidate diagnostic markers of malaria (Publications)
Despite immense efforts to combat malaria in tropical and sub-tropical regions, the potency of this vector-borne disease and its status as a major driver of morbidity and mortality remain undisputed. We
Geostatistical modelling of the malaria risk in Mozambique: effect of the spatial resolution when using remotely-sensed imagery (Publications)
literature exists on the relationship between malaria and environmental/climatic factors in different geographical areas, but few studies have linked human malaria parasitemia survey data with remote sensi [...] The study of malaria spatial epidemiology has benefited from recent advances in geographic information system and geostatistical modelling. Significant progress in earth observation technologies has led [...] classes and assess the effect of the spatial resolution of remotely sensed land...
Assessing the relationship between environmental factors and malaria vector breeding sites in Swaziland using multi-scale remotely sensed data (Publications)
Many entomological studies have analyzed remotely sensed data to assess the relationship between malaria vector distribution and the associated environmental factors. However, the high cost of remotely
High prevalence of malaria in Zambezia, Mozambique: the protective effect of IRS versus increased risks due to pig-keeping and house construction (Publications)
high in many parts of the continent. This study investigated risk factors for malaria infection in children using three malaria indicator surveys from Zambezia province, Mozambique. The impact of IRS and [...] screened for malaria by rapid diagnostic tests. Caregiver interviews were used to assess household demographic and wealth characteristics and ITN and IRS coverage. Associations between malaria infection, [...] versus small households (1-4 persons). CONCLUSION: Malaria infection among...
Strategic roles for behaviour change communication in a changing malaria landscape (Publications)
quality strategic behaviour change communication (BCC) can improve malaria prevention and treatment behaviours. As progress is made towards malaria elimination, BCC becomes an even more important tool. BCC can [...] infections and their compliance with treatment, 3) to inform communities of the optimal timing of malaria control interventions, and 4) to explain changing diagnostic concerns (e.g. increasing false negatives [...] this commentary is to highlight the benefits and value for money that...
Impact of artemisinin-based combination therapy and insecticide-treated nets on malaria burden in Zanzibar (Publications)
The Roll Back Malaria strategy recommends a combination of interventions for malaria control. Zanzibar implemented artemisinin-based combination therapy (ACT) for uncomplicated malaria in late 2003 and [...] all malaria patients, while LLINs are distributed free to children under age 5 y ("under five") and pregnant women. We investigated temporal trends in Plasmodium falciparum prevalence and malaria-related [...] y) mortality decreased by 52%, 33%, and 71%, respectively. Similarly, malaria-rel...
Coverage, adherence and costs of intermittent preventive treatment of malaria in children employing different delivery strategies in Jasikan, Ghana (Publications)
t preventive treatment of malaria in children (IPTc) involves the administration of a course of anti-malarial drugs at specified time intervals to children at risk of malaria regardless of whether or not [...] known to be infected. IPTc provides a high level of protection against uncomplicated and severe malaria, with monthly sulphadoxine-pyrimethamine plus amodiaquine (SP&AQ) and sulphadoxine-pyrimethamine
Pyrethroid resistance in <em>Anopheles gambiae</em>, in Bomi County, Liberia, compromises malaria vector control (Publications)
the efficacy of malaria strategies relying on this class of insecticide. The findings highlight the urgent need to expand and sustain monitoring of insecticide resistance in Liberian malaria vectors, evaluate [...] Lasting Insecticidal Nets (LLIN) and Indoor Residual Spraying (IRS) have both proven to be effective malaria vector control strategies in Africa and the new technology of insecticide treated durable wall lining [...] is logistically challenging and, furthermore, the increase in...
Implementing ideal health policy in a fragile health system: the example of expanding the use of malaria rapid diagnostic tests in mainland Tanzania (Publications)
Malaria confirmation before treatment provides an opportunity for improving the quality of malaria case management in endemic regions. However, increased coverage of this strategy is facing many organizational [...] Introducing an intervention with system-wide effect, such as the use of malaria rapid diagnostic tests in areas where malaria is still a public health problem, should be accompanied by system strengthening