Induction of parasite growth-inhibitory antibodies by a virosomal formulation of a peptidomimetic of loop I from domain III of <em>Plasmodium... (Publications)
membrane antigen 1 (AMA-1) of Plasmodium falciparum is a leading candidate antigen for inclusion in a malaria subunit vaccine. Its ectodomain can be divided into three subdomains, each with disulfide bond-stabilized
First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarials (Publications)
progression to Phase 2a proof-of concept studies in the target population of acute uncomplicated malaria
Synthesis and antimalarial and antituberculosis activities of a series of natural and unnatural 4-methoxy-6-styryl-pyran-2-ones, dihydro analogues and... (Publications)
of this latter scaffold could lead to the identification of new leads for the dual treatment of malaria and leishmaniasis
Population pharmacokinetics of antimalarial naphthoquine in combination with artemisinin in Tanzanian children and adults: dose optimization (Publications)
and children over 5 years of age (6 to 10, 11 to 17, and > /=18 years of age) with uncomplicated malaria in Tanzania. The median weights for the three age groups were 20, 37.5, and 55 kg, respectively.
The first molecular detection of <em>Aedes albopictus</em> in Sudan associates with increased outbreaks of chikungunya and dengue (Publications)
As part of our surveys of the invasive malaria vector Anopheles stephensi in four Sudanese states, including North and South Kordofan, Sennar, and White Nile, we collected 166 larvae. Our morphological
The impact of health worker absenteeism on patient health care seeking behavior, testing and treatment: a longitudinal analysis in Uganda (Publications)
odds that a patient seeks care in the public sector (OR = 0.65, 95% CI = 0.44-0.95) and receives malaria testing (OR = 0.73, 95% CI = 0.53-0.99) and increases the odds of paying out-of-pocket for treatment
Pre-referral rectal artesunate is no "magic bullet" in weak health systems (Publications)
Severe malaria is a potentially fatal condition that requires urgent treatment. In a clinical trial, a sub-group of children treated with rectal artesunate (RAS) before being referred to a health facility
<em>Plasmodium vivax</em> diversity and population structure across four continents (Publications)
Plasmodium vivax is the geographically most widespread human malaria parasite. To analyze patterns of microsatellite diversity and population structure across countries of different transmission intensity
Anti-trypanosomatid elemanolide sesquiterpene lactones from<em> Vernonia lasiopus </em>O. Hoffm (Publications)
Asteraceae family, has been extensively reported to be used ethno-medicinally as a treatment for malaria. Its crude extracts obtained with solvents of different polarity were screened in vitro for anti
Can school-based distribution be used to maintain coverage of long-lasting insecticide treated bed nets: evidence from a large scale programme in... (Publications)
achieved substantial gains in insecticide treated bednet coverage since 2005. The Tanzania National Malaria Control Programme identified school-based net distribution as one potential 'keep-up' strategy for