Malaria transmission dynamics surrounding the first nationwide long-lasting insecticidal net distribution in Papua New Guinea (Publications)
BACKGROUND: The major malaria vectors of Papua New Guinea exhibit heterogeneities in distribution, biting behaviour and malaria infection levels. Long-lasting, insecticide-treated nets (LLINs), distributed [...] distributed as part of the National Malaria Control Programme, are the primary intervention targeting malaria transmission. This study evaluated the impact of LLINs on anopheline density, species composition [...] n, feeding behaviour, and malaria transmission. METHODS: Mosquitoes were...
The time-course of protection of the RTS,S vaccine against malaria infections and clinical disease (Publications)
BACKGROUND: Recent publications have reported follow-up of the RTS,S/AS01 malaria vaccine candidate Phase III trials at 11 African sites for 32 months (or longer). This includes site- and time-specific [...] Bayesian fitting of these model predictions to the site- and time-specific incidence of clinical malaria over 32 months (or longer) of follow-up. Using the same stochastic models, projections of clinical
Epidemiology of malaria in the Taabo health and demographic surveillance system, south-central Côte d'Ivoire (Publications)
epidemiology of malaria is essential for the design and implementation of setting-specific control and elimination efforts. In Cote d'Ivoire, new initiatives are underway to reduce the burden of malaria, which [...] which requires high-quality longitudinal data. The epidemiology of malaria was studied in the Taabo health and demographic surveillance system (HDSS) in south-central Cote d'Ivoire and implications for control [...] 6 and 62.8 % versus 42.6 and 51.2 %; respectively, in 2010 and 2011;...
Efficacy and safety of intermittent preventive treatment with sulfadoxine-pyrimethamine for malaria in African infants: a pooled analysis of six... (Publications)
BACKGROUND: Intermittent preventive treatment (IPT) is a promising strategy for malaria control in infants. We undertook a pooled analysis of the safety and efficacy of IPT in infants (IPTi) with sulf [...] delivered by WHO's Expanded Program on Immunization. Data from the trials for incidence of clinical malaria, risk of anaemia (packed-cell volume