The sensitivity of the OptiMAL rapid diagnostic test to the presence of <em>Plasmodium falciparum </em>gametocytes compromises its ability to monitor... (Publications)
Using in vivo samples from treatment failure malaria cases, we demonstrate the high sensitivity of the parasite lactase dehydrogenase (pLDH)-based OptiMAL rapid diagnostic test in the detection of P.
High throughput multiplex assay for species identification of Papua New Guinea malaria vectors: members of the <em>Anopheles punctulatus</em>... (Publications)
Malaria and filariasis are transmitted in the Southwest Pacific region by Anopheles punctulatus sibling species including An. punctulatus, An. koliensis, the An. farauti complex 1-8 (includes An. hinesorum
Epidemiology of malaria in the Papua New Guinean highlands (Publications)
Below 1400 m, malaria was a significant source of febrile illness. At higher altitudes, malaria was only a significant source of febrile illness during epidemic outbreaks, but asymptomatic malaria infections [...] investigation of the epidemiology of malaria in the Papua New Guinea (PNG) highlands and provide a basis for evidence-based planning and monitoring of intensified malaria control activities. Methods Between [...] and July 2005, 153 household-based, rapid malaria population surveys were...
Effect of interventions to reduce malaria incidence among military personnel on active duty: study protocol for a cluster randomised controlled trial... (Publications)
studies assessing the impact on malaria infection. This study will estimate the protective efficacy of treated uniforms and DEET insect repellent on the incidence of malaria infection among military personnel [...] placebo-controlled trial is planned to evaluate the effectiveness of the interventions on preventing malaria infections in soldiers on active duty at Mgambo National Service Camp in Tanga, Tanzania. The arms [...] untreated uniforms with placebo lotion. The primary outcome is the...
Insights from modelling malaria vaccines for policy decisions: the focus on RTS,S (Publications)
ns. This review illustrates the utility of simulation approaches by reviewing the literature on malaria vaccine modelling, with a focus on its link to the development of policy guidance for the first licensed
Prevalence and risk factors for malaria in pregnancy in Vanga, Democratic Republic of Congo (Publications)
(DRC) is the second most malarious country in the world, but little information is available on malaria control measures in pregnancy. We conducted a longitudinal study among 395 women pregnant with singletons [...] Vanga Health Zone, Kwilu Province. We recruited 406 pregnant women between April and October 2019. Malaria prevalence at recruitment was 18.8% in Vanga and 30.1% in Mayoko (difference p
Delayed cerebellar ataxia, a rare post-malaria neurological complication: case report and review of the literature (Publications)
Delayed cerebellar ataxia (DCA) is a rare post-malarial neurological complication with unknown pathomechanism characterized by its self-limiting course and favorable outcome. We report a case of DCA f
Infectivity of symptomatic malaria patients to <em>Anopheles farauti</em> colony mosquitoes in Papua New Guinea (Publications)
to mosquitoes is an understudied bottleneck in the transmission of malaria. Direct membrane feeding assays (DMFA) allow detailed malaria transmission studies from humans to mosquitoes. Especially for Plasmodium [...] were performed with venous blood collected from rapid diagnostic test (RDT) positive symptomatic malaria patients and subsequently analysed by light microscopy and quantitative real time polymerase chain