Re-estimated equations for 5th percentiles of lung function variables (Letter to editors) (Publications)
In 1996 we published reference equations for the 5th percentiles of lung function parameters (FVC, FEV1, PEF, FEF25, FEF50, FEF75, FEF25-75, FEV1/FVC) as a function of age and height.1 These reference
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function (Publications)
Pulmonary function measures reflect respiratory health and are used in the diagnosis of chronic obstructive pulmonary disease. We tested genome-wide association with forced expiratory volume in 1 seco
Long-term smoking cessation and heart rate dynamics in an aging healthy cohort: is it possible to fully recover? (Publications)
AIM: To evaluate the long-term influence of smoking cessation on the regulation of the autonomic cardiovascular system in an aging general population, using the subpopulation of lifelong non-smokers a
Years of life lost and morbidity cases attributable to transportation noise and air pollution: a comparative health risk assessment for Switzerland in... (Publications)
BACKGROUND: There is growing evidence that chronic exposure to transportation related noise and air pollution affects human health. However, health burden to a country of these two pollutants have bee
Improved air quality and attenuated lung function decline: modification by obesity in the SAPALDIA cohort (Publications)
OBJECTIVE: Air pollution and obesity are hypothesized to contribute to accelerated lung function decline with age through their inflammatory properties. We investigated whether the previously reported
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis (Publications)
Genetic association studies have identified 21 loci associated with atopic dermatitis risk predominantly in populations of European ancestry. To identify further susceptibility loci for this common, c
Agreement between spirometers: a challenge in the follow-up of patients and populations? (Publications)
Background: Long-term cohort studies and lung function laboratories are confronted with the need for replacement of spirometers. Lack of agreement between spirometers might affect the longitudinal com
Genome-wide association study of lung function decline in adults with and without asthma (Publications)
BACKGROUND: Genome-wide association studies have identified determinants of chronic obstructive pulmonary disease, asthma, and lung function level; however, none have addressed decline in lung functio