Forschung für Generationen (Publications)
Die ehemalige "Luft- und Lungen-Studie" SAPALDIA ist 20 Jahre alt geworden. Forscherinnen und Forscher aus verschiedensten Disziplinen untersuchen seit Jahren das Zusammenspiel von Umwelt und Gesundhe
Identification of a new locus at 16q12 associated with time-to-asthma onset (Publications)
BACKGROUND: Asthma is a heterogeneous disease in which age of onset plays an important role. OBJECTIVE: We sought to identify the genetic variants associated with time to asthma onset (TAO). METHODS:
Years of life lost and morbidity cases attributable to transportation noise and air pollution: a comparative health risk assessment for Switzerland in... (Publications)
BACKGROUND: There is growing evidence that chronic exposure to transportation related noise and air pollution affects human health. However, health burden to a country of these two pollutants have bee
Improved air quality and attenuated lung function decline: modification by obesity in the SAPALDIA cohort (Publications)
OBJECTIVE: Air pollution and obesity are hypothesized to contribute to accelerated lung function decline with age through their inflammatory properties. We investigated whether the previously reported
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis (Publications)
Genetic association studies have identified 21 loci associated with atopic dermatitis risk predominantly in populations of European ancestry. To identify further susceptibility loci for this common, c
Genome-wide association study of lung function decline in adults with and without asthma (Publications)
BACKGROUND: Genome-wide association studies have identified determinants of chronic obstructive pulmonary disease, asthma, and lung function level; however, none have addressed decline in lung functio
Variability of reproductive history across the Swiss SAPALDIA cohort - Pattern and main determinants (Publications)
Background: Reproductive characteristics play an aetiological role for many diseases, including reproductive cancers. They have been shown to vary internationally and nationally, but have not yet been
Longitudinal validity of spirometers: a challenge in longitudinal studies (Publications)
QUESTION UNDER STUDY: Pulmonary function testing (PFT) in longitudinal studies involves the repeated use of spirometers over long time periods. We assess the comparability of PFT results taken under b