Genomic deletions classify the Beijing/W strains as a distinct genetic lineage of <em>Mycobacterium tuberculosis</em> (Publications)
Beijing/W strains of Mycobacterium tuberculosis are geographically widespread and hypervirulent. To enhance our understanding of their origin and evolution, we sought phylogenetically informative larg
In vitro antimalarial activity of hyperforin, a prenylated acylphloroglucinol. A structure-activity study (Publications)
The antimalarial activity of hyperforin, a phenol-like compound that can be easily absorbed orally, and a series of derivatives variously modified on the cyclohexatrienone system was investigated. Hyp
Nifurtimox-eflornithine combination therapy for second-stage <em>Trypanosoma brucei gambiense</em> sleeping sickness: a randomized clinical trial in... (Publications)
BACKGROUND: Human African trypanosomiasis caused by Trypanosoma brucei gambiense is a fatal disease. Current treatment options for patients with second-stage disease are either highly toxic or impract
A comparative study of the efficacies of chloroquine and a pyrimethamine-dapsone combination in clearing <em>Plasmodium falciparum</em> parasitaemia... (Publications)
A randomized study on the in vivo efficacies of chloroquine and a pyrimethamine-dapsone combination (Maloprim) in clearing P. falciparum parasitaemia was carried out in 77 asymptomatic semi-immune sch