(+/-)-Alternarlactones A and B, two antiparasitic alternariol-like dimers from the fungus <em>Alternaria alternata</em> p1210 isolated from the... (Publications)
Two new dimeric compounds of the alternariol class, (+/-)-alternarlactones A (1) and B (2), were isolated along with 11 known compounds from the fungus Alternaria alternata P1210. Their structures wer
National and sub-national exposure to ambient fine particulate matter PM2.5 and its attributable burden of disease in Iran from 1990 to 2016 (Publications)
Ambient particulate matter is a public health concern. We aimed (1) to estimate national and provincial long-term exposure of Iranians to ambient particulate matter (PM)
Impact of environmental changes on infectious diseases: key findings from an international conference in Trieste, Italy in May 2017 (Publications)
Elsevier's 2(nd) conference on "Impact of Environmental Changes on Infectious Diseases" (IECID), convened in May 2017 in Trieste, Italy, brought together some 120 researchers from more than 20 countri
Reasons for prehospital delay in acute ischemic stroke (Publications)
Background Prehospital delay reduces the proportion of patients with stroke treated with recanalization therapies. We aimed to identify novel and modifiable risk factors for prehospital delay. Methods
Exogenous iron increases fasciocidal activity and hepatocellular toxicity of the synthetic endoperoxides OZ78 and MT04 (Publications)
The synthetic peroxides OZ78 and MT04 recently emerged as fasciocidal drug candidates. However, the effect of iron on fasciocidal activity and hepatocellular toxicity of these compounds is unknown. We
Animal-assisted therapy for patients in a minimally conscious state: a randomized two treatment multi-period crossover trial (Publications)
OBJECTIVE: To investigate if animal-assisted therapy (AAT) leads to higher consciousness in patients in a minimally conscious state during a therapy session, measured via behavioral reactions, heart r
Case report: human subcutaneous sparganosis in a Thai migrant (Publications)
Human sparganosis is a cestode infection which is neglected as a differential diagnosis outside endemic countries. Diagnosis and therapy may be challenging depending on the clinical presentation and a
Pulmonary cryptococcosis: report of the first confirmed autochthonous case in Nepal (Publications)
We report a case of cryptococcal pneumonia in a 53 years old female Nepali patient with uncontrolled diabetes mellitus type 2 who empirically received multiple broad-spectrum antibiotics and standard
Physiologically based pharmacokinetic modelling to identify pharmacokinetic parameters driving drug exposure changes in the elderly (Publications)
BACKGROUND: Medication use is highly prevalent with advanced age, but clinical studies are rarely conducted in the elderly, leading to limited knowledge regarding age-related pharmacokinetic changes.