Ivermectin treatment and sanitation effectively reduce <em>Strongyloides stercoralis</em> infection risk in rural communities in Cambodia (Publications)
BACKGROUND: Strongyloides stercoralis is the only soil-transmitted helminth with the ability to replicate within its host, leading to long-lasting and potentially fatal infections. It is ubiquitous an
Host-directed therapies for infectious diseases: current status, recent progress, and future prospects (Publications)
Despite extensive global efforts in the fight against killer infectious diseases, they still cause one in four deaths worldwide and are important causes of long-term functional disability arising from
Population pharmacokinetic modeling of tribendimidine metabolites in <em>Opisthorchis viverrini</em>-infected adults (Publications)
There is a pressing need for alternative treatments against the liver fluke Opisthorchis viverrini Oral tribendimidine is a promising candidate, but its population pharmacokinetic properties are unkno
Comparison of sensitivity and faecal egg counts of mini-FLOTAC using fixed stool samples and Kato-Katz technique for the diagnosis of <em>Schistosoma... (Publications)
Accurate diagnostic tools for human helminthiasis are crucial for improved patient management and evaluation of community-based intervention studies. However, the diagnosis of intestinal schistosomias
Evaluation of malaria diagnoses using a handheld light microscope in a community-based setting in rural Côte d'Ivoire (Publications)
Portable microscopy may facilitate quality diagnostic care in resource-constrained settings. We compared a handheld light microscope (Newton Nm1) with a mobile phone attachment to conventional light m
Antibody-mediated neutralization of the exotoxin mycolactone, the main virulence factor produced by <em>Mycobacterium ulcerans</em> (Publications)
BACKGROUND: Mycolactone, the macrolide exotoxin produced by Mycobacterium ulcerans, causes extensive tissue destruction by inducing apoptosis of host cells. In this study, we aimed at the production o
Non-vector-borne transmission of Zika virus: a systematic review (Publications)
BACKGROUND: Increasing numbers of confirmed cases of Zika virus (ZIKV) infection resulting from non-mosquito-borne transmission have been reported. METHODS: We performed a systematic literature review
Severe malaria in Europe: an 8-year multi-centre observational study (Publications)
BACKGROUND: Malaria remains one of the most serious infections for travellers to tropical countries. Due to the lack of harmonized guidelines a large variety of treatment regimens is used in Europe to