Pharmacokinetics of the antischistosomal lead ozonide OZ418 in uninfected mice determined by liquid chromatography-tandem mass spectrometry (Publications)
One of the major neglected tropical diseases, schistosomiasis, is currently treated and controlled with a single drug, praziquantel. The quest for an alternative drug is fueled by its lack of activity
Influenza pandemics and tuberculosis mortality in 1889 and 1918: analysis of historical data from Switzerland (Publications)
BACKGROUND: Tuberculosis (TB) mortality declined in the northern hemisphere over the last 200 years, but peaked during the Russian (1889) and the Spanish (1918) influenza pandemics. We studied the imp
Detection and characterization of drug-resistant conferring genes in <em>Mycobacterium tuberculosis</em> complex strains: a prospective study in two... (Publications)
We spoligotyped and screened 1490 clinical Mycobacterium tuberculosis complex strains from Northern and Greater Accra regions of Ghana against INH and RIF using the microplate alamar blue phenotypic a
Exposure to ambient air pollution and the risk of inflammatory bowel disease: a European nested case-control study (Publications)
BACKGROUND: Industrialization has been linked to the etiology of inflammatory bowel disease (IBD). AIM: We investigated the association between air pollution exposure and IBD. METHODS: The European Pr
cART prescription trends in a prospective HIV cohort in rural Tanzania from 2007 to 2011 (Publications)
BACKGROUND: Since 2010, World Health Organization (WHO) guidelines discourage using stavudine in first-line regimens due to frequent and severe side effects. This study describes the implementation of
Indoloditerpenes from a marine-derived fungal strain of <em>Dichotomomyces cejpii</em> with antagonistic activity at GPR18 and cannabinoid receptors (Publications)
A marine-derived strain of Dichotomomyces cejpii produces the new compounds emindole SB beta-mannoside (1) and 27-O-methylasporyzin C (2), as well as the known indoloditerpenes JBIR-03 (3) and emindol