The burden of leprosy in Cameroon: fifteen years into the post-elimination era (Publications)
BACKGROUND: Cameroon achieved the elimination target of leprosy in 2000, and has maintained this status ever since. However, a number of health districts in the country continue to report significant
2-Octadecynoic acid as a dual life stage inhibitor of <em>Plasmodium</em> infections and plasmodial FAS-II enzymes (Publications)
The malaria parasite Plasmodium goes through two life stages in the human host, a non-symptomatic liver stage (LS) followed by a blood stage with all clinical manifestation of the disease. In this stu
Examples of coupled human and environmental systems from the extractive industry and hydropower sector interfaces (Publications)
Large-scale corporate projects, particularly those in extractive industries or hydropower development, have a history from early in the twentieth century of creating negative environmental, social, an
Raising more domestic money for health: prospects for low- and middle-income countries (Publications)
Since the 2007/2008 financial crisis, the rhetoric in the development assistance dialogue has shifted away from raising more international funding for health, to requesting countries to move toward se
Exposure of <em>Heligmosomoides polygyrus</em> and <em>Trichuris muris</em> to albendazole, albendazole sulfoxide, mebendazole and oxantel pamoate... (Publications)
Millions of people are treated with anthelmintics to control soil-transmitted helminth infections; yet, drug distribution in the plasma and gastrointestinal tract compartments and the pathway of drug
Monitoring of selected health indicators in children living in a copper mine development area in northwestern Zambia (Publications)
The epidemiology of malaria, anaemia and malnutrition in children is potentially altered in mining development areas. In a copper extraction project in northwestern Zambia, a health impact assessment
Low efficacy of albendazole against <em>Trichuris trichiura</em> infection in schoolchildren from Port Elizabeth, South Africa (Publications)
BACKGROUND: Albendazole is one of two standard drugs for the control of soil-transmitted helminthiasis. METHODS: A total of 149 schoolchildren from Port Elizabeth, South Africa, were examined for soil
Antimalarial pyrido[1,2-a]benzimidazoles: lead optimization, parasite life cycle stage profile, mechanistic evaluation, killing kinetics, and <em>in... (Publications)
Further structure-activity relationship (SAR) studies on the recently identified pyrido[1,2-a]benzimidazole (PBI) antimalarials have led to the identification of potent, metabolically stable compounds