Evaluation of giant African pouched rats for detection of pulmonary tuberculosis in patients from a high-endemic setting (Publications)
BACKGROUND: This study established evidence about the diagnostic performance of trained giant African pouched rats for detecting Mycobacterium tuberculosis in sputum of well-characterised patients wit
cART prescription trends in a prospective HIV cohort in rural Tanzania from 2007 to 2011 (Publications)
Comprehensive information on combined antiretroviral therapy (cART) regimens in rural Sub-Saharan Africa over time is scarce, particularly on the use of stavudine (d4T) and second-line regimens. Since
Impact of traffic-related air pollution on acute changes in cardiac autonomic modulation during rest and physical activity: a cross-over study (Publications)
People are often exposed to traffic-related air pollution (TRAP) during physical activity (PA), but it is not clear if PA modifies the impact of TRAP on cardiac autonomic modulation. We conducted a pa
Match-making for pasaconazole through systems thinking (Publications)
Currently available drugs for Chagas' disease are limited by toxicity and low efficacy in the chronic stage. Posaconazole, the most advanced new anti-chagasic drug candidate, did not fully confirm its
Structure-activity relationship studies of orally active antimalarial 2,4-diamino-thienopyrimidines (Publications)
Based on the initial optimization of orally active antimalarial 2,4-diamino-thienopyrimidines and with the help of metabolite identification studies, a second generation of derivatives involving chang
Evaluation of portable microscopic devices for the diagnosis of Schistosoma and soil-transmitted helminth infection (Publications)
SUMMARY The diagnosis of parasitic worm (helminth) infections requires specialized laboratory settings, but most affected individuals reside in locations without access to such facilities. We tested t
System effectiveness of a targeted free mass distribution of long lasting insecticidal nets in Zanzibar, Tanzania (Publications)
BACKGROUND: Insecticide-treated nets (ITN) and long-lasting insecticidal treated nets (LLIN) are important means of malaria prevention. Although there is consensus regarding their importance, there is