Discovery of antischistosomal drug leads based on tetraazamacrocyclic derivatives and their metal complexes (Publications)
Praziquantel (PZQ) is the only available drug to treat schistosomiasis, and since its large scale use might be associated with the onset of resistance, new antischistosomal drugs should be developed.
School distribution as keep-up strategy to maintain universal coverage of long-lasting insecticidal nets: implementation and results of a program in... (Publications)
Tanzania successfully scaled up coverage of long-lasting insecticidal nets (LLINs) through mass campaigns. To sustain these gains, a school-based approach was piloted in the country's Southern Zone st
Successful comeback of the single-dose live oral cholera vaccine CVD 103-HgR (Publications)
Effective and easy to administer cholera vaccines are in need more than ever, for at risk populations and travellers alike. In many parts of the world cholera is still endemic, causing outbreaks and c
Evaluation of the in vivo activity of tribendimidine against <em>Schistosoma mansoni, Fasciola hepatica, Clonorchis sinensis,</em> and... (Publications)
We examined the in vivo activity of tribendimidine against selected trematodes. A single 150-mg/kg dose of tribendimidine achieved a 99.1% reduction of Clonorchis sinensis in rats. A 400-mg/kg dose of
Untapped potential of health impact assessment (Publications)
The World Health Organization has promoted health impact assessment (HIA) for over 20 years. At the 2012 United Nations Conference on Sustainable Development (Rio+20), HIA was discussed as a critical
Facile synthesis of cyclohexanediones and dialkylresorcinols - bioactive natural products from entomopathogenic bacteria [Short communication] (Publications)
A synthesis for the recently identified, widespread bacterial natural product classes of dialkylresorcinols and cyclohexanediones was developed. The synthesis route is similar to the biosynthesis rout
Health-related quality of life in rural children living in four European countries: the GABRIEL study (Publications)
OBJECTIVE: Measuring children's health-related quality of life (HRQOL) is of growing importance given increasing chronic diseases. By integrating HRQOL questions into the European GABRIEL study, we as