Genetic diversity in <em>Mycobacterium tuberculosis</em> (Publications)
Recent years have witnessed an increased appreciation of the extent and relevance of strain-to-strain variation in Mycobacterium tuberculosis. This paradigm shift can largely be attributed to an impro
Evaluation of land use regression models for NO2 and particulate matter in 20 European study areas: the ESCAPE project (Publications)
Land use regression models (LUR) frequently use leave-one-out-cross-validation (LOOCV) to assess model fit, but recent studies suggested that this may overestimate predictive ability in independent da
Role of highway traffic on spatial and temporal distributions of air pollutants in a Swiss alpine valley (Publications)
Traffic-related air pollutants show high spatial variability near roads, posing a challenge to adequately assess exposures. Recent modeling approaches (e.g. dispersion models, land-use regression (LUR
Inhibitors of adenosine consuming parasites through polymer-assisted N-acylation of N6-substituted 5'-amino-5'-deoxyadenosines (Publications)
A series of 30 adenosine derivatives with three different substituents at the N(6)-position were prepared in order to evaluate their potential to inhibit the pathogenic protozoa Plasmodium falciparum
Immune recovery after starting ART in HIV-infected patients presenting and not presenting with tuberculosis in south Africa (Publications)
We studied the immune response after starting antiretroviral treatment (ART) in 15,646 HIV-infected patients with or without tuberculosis (TB) at presentation in 3 ART programs in South Africa between
Effects of inflammation and <em>Plasmodium falciparum</em> infection on soluble transferrin receptor and plasma ferritin concentration in different... (Publications)
BACKGROUND: Iron deficiency (ID) is a major cause of anemia, along with other nutritional, parasitic, and genetic factors. Accurate biomarkers are needed to estimate the relative contribution of ID to
Neue genetische Tests und ihr Nutzen in der Krebsvorsorge (Publications)
The promises resulting from the decoding of the human genome have not been fulfilled to the extent as expected. At the same time it is fair to say that the results of recent genetic research have not