Oma1, a novel membrane-bound metallopeptidase in mitochondria with activities overlapping with the m-AAA protease (Publications)
The integrity of the inner membrane of mitochondria is maintained by a membrane-embedded quality control system that ensures the removal of misfolded membrane proteins. Two ATP-dependent AAA proteases
Differential gene repertoire in <em>Mycobacterium ulcerans</em> identifies candidate genes for patho-adaptation (Publications)
BACKGROUND: Based on large genomic sequence polymorphisms, several haplotypes belonging to two major lineages of the human pathogen Mycobacterium ulcerans could be distinguished among patient isolates
Single nucleotide polymorphisms on the road to strain differentiation in <em>Mycobacterium ulcerans</em> (Publications)
The genomic fine-typing of strains of Mycobacterium ulcerans, the causative agent of the emerging human disease Buruli ulcer, is difficult due to the clonal population structure of geographical lineag
Optimized method for preparation of DNA from pathogenic and environmental mycobacteria (Publications)
Genomic studies on pathogenic and environmental mycobacteria are of growing interest for understanding of their evolution, distribution, adaptation, and host-pathogen interaction. Since most mycobacte
Gesundheit als soziale Aufgabe (Publications)
Die weltweite Gesundheitsversorgung wird zu einem zunehmend wichtigeren Anliegen. Wer in einkommensschwachen Ländern medizinisch tätig sein oder sich anderweitig mit globalen Gesundheitsfragen beschäf
Survived infancy but still vulnerable: spatial-temporal trends and risk factors for child mortality in the Agincourt rural sub-district, South Africa,... (Publications)
Targeting of health interventions to poor children at highest risk of mortality are promising approaches for enhancing equity. Methods have emerged to accurately quantify excess risk and identify spac