How to evaluate health-related quality of life and its association with medication adherence in pulmonary tuberculosis - designing a prospective... (Publications)
INTRODUCTION: Health-related quality of life (HRQOL) has become an important measure to identify and shape effective and patient-relevant healthcare interventions innovations through outcomes. Adheren
<em>IL-33</em> polymorphisms are associated with increased risk of hay fever and reduced regulatory T cells in a birth cohort (Publications)
BACKGROUND: IL-33 polymorphisms influence the susceptibility to asthma. IL-33 indirectly induces Th2-immune responses via dendritic cell activation, being important for development of atopic diseases.
Standard genotyping overestimates transmission of <em>Mycobacterium tuberculosis</em> among immigrants in a low incidence country (Publications)
Immigrants from high tuberculosis (TB) incidence regions are a risk group for TB in low-incidence countries such as Switzerland. In a previous analysis of a nationwide collection of 520 Mycobacterium
Ultrasonography of gallbladder abnormalities due to schistosomiasis (Publications)
After malaria, schistosomiasis remains the most important tropical parasitic disease in large parts of the world. Schistosomiasis has recently re-emerged in Southern Europe. Intestinal schistosomiasis
Quinolone amides as anti-trypanosomal lead compounds with in vivo activity (Publications)
Human African Trypanosomiasis (HAT) is a major tropical disease with few available drugs for treatment driving the need for novel active compounds. Recently, morpholino-substituted benzyl amides of th
Drug resistance mutations after the first 12 months on antiretroviral therapy and determinants of virologic failure in Rwanda (Publications)
OBJECTIVE: To evaluate HIV drug resistance (HIVDR) and determinants of virological failure in a large cohort of patients receiving first-line tenofovir-based antiretroviral (ART) regimens. METHODS: A
Giant host red blood cell membrane mimicking polymersomes bind parasite proteins and malaria parasites (Publications)
Malaria is an infectious disease that needs to be addressed using innovative approaches to counteract spread of drug resistance and to establish or optimize vaccination strategies. With our approach,
Reliability of functional connectivity of EEG applying microstates-segmented versus classical calculation of phase lag index (Publications)
BACKGROUND: Connectivity analysis characterizes normal and altered brain function, e.g. using the phase lag index (PLI), which is based on phase relations. However, reliability of PLI over time is lim
Microbial contamination along the main open wastewater and storm water channel of Hanoi, Vietnam, and potential health risks for urban farmers (Publications)
The use of wastewater in agriculture and aquaculture has a long tradition throughout Asia. For example, in Hanoi, it creates important livelihood opportunities for > 500,000 farmers in peri-urban comm