Bovine tuberculosis at a cattle-small ruminant-human interface in Meskan, Gurage region, central Ethiopia (Publications)
ABSTRACT: BACKGROUND: Bovine tuberculosis (BTB) is endemic in Ethiopian cattle. The aim of this study was to assess BTB prevalence at an intensive contact interface in Meskan Woreda (district) in catt
Sir2 paralogues cooperate to regulate virulence genes and antigenic variation in <em>Plasmodium falciparum</em> (Publications)
Cytoadherance of Plasmodium falciparum-infected erythrocytes in the brain, organs and peripheral microvasculature is linked to morbidity and mortality associated with severe malaria. Parasite-derived
Pharmacology of DB844, an orally active aza analogue of pafuramidine, in a monkey model of second stage human African trypanosomiasis (Publications)
Novel drugs to treat human African trypanosomiasis (HAT) are still urgently needed despite the recent addition of nifurtimox-eflornithine combination therapy (NECT) to WHO Model Lists of Essential Med
Evidence of blood stage efficacy with a virosomal malaria vaccine in a phase IIa clinical trial (Publications)
BACKGROUND: Previous research indicates that a combination vaccine targeting different stages of the malaria life cycle is likely to provide the most effective malaria vaccine. This trial was the firs
Structure-activity relationship studies on the macrolide exotoxin mycolactone of <em>Mycobacterium ulcerans</em> (Publications)
BACKGROUND: Mycolactones are a family of polyketide-derived macrolide exotoxins produced by Mycobacterium ulcerans, the causative agent of the chronic necrotizing skin disease Buruli ulcer. The toxin
Health-related quality of life in migrant preschool children (Publications)
BACKGROUND: Minority groups have a lower health-related quality of life (HRQOL), but there is little information if this finding also applies to children. In this study, we compared HRQOL between youn
Analysing and recommending options for maintaining universal coverage with long-lasting insecticidal nets: the case of Tanzania in 2011 (Publications)
BACKGROUND: Tanzania achieved universal coverage with long-lasting insecticidal nets (LLINs) in October 2011, after three years of free mass net distribution campaigns and is now faced with the challe
A large scale gene-centric association study of lung function in newly-hired female cotton textile workers with endotoxin exposure (Publications)
BACKGROUND: Occupational exposure to endotoxin is associated with decrements in pulmonary function, but how much variation in this association is explained by genetic variants is not well understood.